• Gopal Jee
• Rakesh Kumar Singh
• Anjani Kumr Shukla
• Kumari Sweeti

Heterocyclic compounds containing nitrogen and Oxygen as hetero atoms are an important class of compounds largely employed in pharmaceutical and therapeutic field. The present paper deals with the synthesis of 3, 5-disubstituted isoxazoles from substituted phenyl pyrone-2 on treatment with hydroxyl amine hydrochloride on irradiation in microwave. This method of ring transformation is a deviation from the classical synthetic procedure.

Heterocyclic compounds, Pharmaceutical, pyrone-2, hydroxylamine hydrochloride, irradiation, isoxazole.

"Synthesis of some isoxazole derivatives by ring transformation of pyrone-2", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.4, Issue 10, page no.765-767, October 2017, Available :http://www.jetir.org/papers/JETIR1710117.pdf

"Synthesis of some isoxazole derivatives by ring transformation of pyrone-2", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.4, Issue 10, page no. pp765-767, October 2017, Available at : http://www.jetir.org/papers/JETIR1710117.pdf