• Meenu Narwal
• Tapan kumar Mukherjee
• Rajasri Bhattacharyya

Human serum albumin (HSA) is an opulent, non- glycosylated, most versatile carrier protein in plasma possessing multiple functions. It comprehends of multiple binding sites located in different subdomains and are responsible for binding of ligands. While antecedent research have discovered various functional and structural properties of HSA, the objective of this review paper is to shed light on some of the important properties of HSA and how binding pattern of different ligands can sustain the development of new drugs. Some significant properties include transportation, ligand- binding, distribution and metabolism of a compound. It also undergoes glycation and acts as an antioxidant. Another important feature is an esterase- like activity possessed by HSA, which is also crucial in converting the prodrugs into active theraupetics. Therefore, HSA is one of the most suitable molecule for future research in drug discovery in pharmaceutical industry because of its numerous features and binding pattern that also governs the metabolism and drug dosage.

Human serum albumin, ligand- binding, esterase –like activity

"Insight Into Properties Of Human Serum Albumin For Novel Drug Discoveries", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.4, Issue 11, page no.802-807, December-2017, Available :http://www.jetir.org/papers/JETIR1711136.pdf

"Insight Into Properties Of Human Serum Albumin For Novel Drug Discoveries", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.4, Issue 11, page no. pp802-807, December-2017, Available at : http://www.jetir.org/papers/JETIR1711136.pdf