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Calcium homeostasis: the mitochondrial target and interaction with hormones

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Abstract—Intracellular calcium regulates a wide variety of physiological processes. Mitochondria cannot be considered as a static structure, as changes in cytoplasmic Ca2+ concentration, resulting from activation of intracellular Ca2+ channels within the mitochondria, regulate several aspects of cell regulatory and signaling events. Well beyond its critical bioenergetic role in supplying ATP, mitochondria act as the centre of many diverse cellular functions, which integrate the signals between the organellae and the nucleus. In addition, a close relationship exists between mitochondrial bioenergetic pathways and calcium transport, which both may demand to activate cell signaling events. Thus, mitochondrial target in calcium homeostasis appears to be a prerequisite for proper functioning of the cell.

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Mitochondria, Calcium, Ion homeostasis, Calcium uniporter, Hormones.

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"Calcium homeostasis: the mitochondrial target and interaction with hormones", International Journal of Emerging Technologies and Innovative Research ( | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 1, page no. pp300-304, January-2018, Available at : &

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Published Paper ID: JETIR1801059
Registration ID: 180026
Published In: Volume 5 | Issue 1 | Year January-2018
DOI (Digital Object Identifier):
Page No: 300-304
ISSN Number: 2349-5162

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(Volume 5 | Issue 1 | January 2018 |Impact factor 5.87)

Call For Paper | Volume 5 | Issue 1 | Impact factor 5.87

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