UGC Approved Journal no 63975(19)

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Published in:

Volume 5 Issue 3
March-2018
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1803061


Registration ID:
180610

Page Number

307-311

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Title

Therapeutic alternatives against Helicobacter pylori eradication rate improved with herbal therapy regimen

Abstract

Most of the drugs today are obtained from natural sources or semi synthetic derivatives of natural products used in the traditional systems of medicine. Treatment of Helicobacter pylori infection is one of the effective ways to prevent gastric cancer. Present work focused for the combination of  -carotene and Plumbagin administrated to Helicobacter pylori infected mice and that eradication of this organism greatly reduces the recurrence rate of ulcers. Purification of  -carotene from carrot and isolation of Plumbagin from Plumbago zeylanica were simportant bioactive material being used to treat H. pylori infection which caused gastric cancer and peptic ulcer disease in the traditional system of medicines. β- carotene is an antioxidant isolated from carrot and quantified exactly in different steps of purification, the yield of pure β-Carotene was high when it prepared with ethanol extraction proved the recovery of HPLC separation methods. The mouse were divided into four groups comprising of five animals in each group and designated as follows: Control, H. pylori infected animals, H. pylori infected animals treated with plumbagin, β- carotene alone and combination of both plumbagin & β- carotene .At the end of the experimental period, analysis carried out with gastric tissues and the repair responses to this injury were assessed with standard omeprazole. Preliminary screening was made by the disk diffusion test and then minimum inhibitory concentration was determined by the agar dilution method. Alternative eradication therapies, which consist of two plant based purified bioactive compound are highly effective, based on western blot expression of IL-6 confirmed eradicating H. pylori also capable of inhibiting the in vitro growth of H. pylori has investigated.

Key Words

Therapeutic alternatives against Helicobacter pylori eradication rate improved with herbal therapy regimen

Cite This Article

"Therapeutic alternatives against Helicobacter pylori eradication rate improved with herbal therapy regimen", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 3, page no.307-311, March-2018, Available :http://www.jetir.org/papers/JETIR1803061.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Therapeutic alternatives against Helicobacter pylori eradication rate improved with herbal therapy regimen", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 3, page no. pp307-311, March-2018, Available at : http://www.jetir.org/papers/JETIR1803061.pdf

Publication Details

Published Paper ID: JETIR1803061
Registration ID: 180610
Published In: Volume 5 | Issue 3 | Year March-2018
DOI (Digital Object Identifier):
Page No: 307-311
Country: -, -, - .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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