• SAIMA MOHIUDIN
• MOHAMAD ANAS
• ARJUMAND BANO

Therapeutic Effect of Tukhm-e-Hayat (Withania coagulans) in the Management of Pre-Diabetics (Impaired Fasting Glucose & Impaired Glucose Tolerance). Saima Mohiudin* Mohammad Anas** Arjumand Bano** Department of Moalejat, Ajmal Khan Tibbia College, Aligarh, India. Objectives: Prediabetes is the precursor stage before diabetes mellietus in which all the symptoms of diabetes mellietus are not present, but blood sugar is abnormally high. Prediabetes is not a clinical entity in its own right but rather an increased risk for diabetes and cardiovascular disease. It is a metabolic diathesis .According to the latest survey of W.H.O the burden of prediabetics is more than diabetics which will soon be converted into indolent diabetes. Thus there is a need to find out the way to lessen this prediabetic burden.The purpose of this study was to determine the effect of Tukhm-e-Hayat for treating Prediabetes & to collect data to warrant further clinical trials. Methods : A case series was conducted with ten (20) patients of IFG & IGT, clinically diagnosed after excluding the possible causes by proper laboratory work-up & confirmed by blood sugar fasting levels and glucose tolerance test, Subsequently patients were treated with Tukhm-e-Hayat . Results : In Patients of both types of Pre-Diabetes (IFG, IGT) , there was significant improvement in blood sugar levels within an average of 4 months treatment. Discussion : The literature review related to Tukhm-e-Hayat used for the treatment in this study, showed that this drug possess anti-inflammatory, analgesic, laxative, antimicrobial & acetylcholine like actions, suggesting possible mechanism of action in Prediabetes. Conclusion: The preliminary findings indicate that Tukhm-e-Hayat is effective in Prediabetes.

KEYWORDS: : Prediabetes, Impaired fasting glucose (IFG), Impaired glucose tolerance (IGT), Tukhm-e-Hayat

"Therapeutic Effect of Tukhm-e-Hayat (Withania coagulans) in the Management of Pre-Diabetics (Impaired Fasting Glucose & Impaired Glucose Tolerance). Saima Mohiudin* Mohammad Anas** Arjumand Bano**", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 3, page no.885-887, March-2018, Available :http://www.jetir.org/papers/JETIR1803169.pdf

"Therapeutic Effect of Tukhm-e-Hayat (Withania coagulans) in the Management of Pre-Diabetics (Impaired Fasting Glucose & Impaired Glucose Tolerance). Saima Mohiudin* Mohammad Anas** Arjumand Bano**", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 3, page no. pp885-887, March-2018, Available at : http://www.jetir.org/papers/JETIR1803169.pdf