Abstract
Abstract
The search for natural products with pharmacological properties has led to the discovery of pharmacologically active substances with significant applications in the experimental and therapeutic arenas. Presently, about 25–30% of all active principles used as therapeutic treatments are extracted from natural products. As more than 70% of the world’s surface is covered by oceans, the wide diversity of marine organisms offers a rich source of natural products. Among marine organisms, marine algae are rich sources of structurally diverse bioactive compounds with various biological activities. Edible marine algae, sometimes referred as seaweeds, have attracted a special interest as good sources of nutrients and one particular interesting feature is their richness in sulfated polysaccharides (SPs), the uses of which span from food, cosmetic and pharmaceutical industries to microbiology and biotechnology. Marine algae are one of the richest sources of structurally diverse natural products. In recent years, an increasing number of novel compounds have been isolated from marine algae and many of them have been reported to possess interesting biological activities. Therefore, it is clearly documented that, pre-clinical pharmacological research with new marine compounds continued to be extremely active in recent history. Red algae are reported to possess a variety of phytoconstituents including phenols, flavonoids, alkaloids, tannins and terpenoids etc. which in turn account for its enormous pharmacological activities. The constituents obtained from red algae enlarge the chemical library and improve the opportunity to discover new pharmaceutical agents, and interesting novel constituents will still be found in the future. Intensive efforts and obvious progress have been made in recent years and provide evidence that constituents from red algae exhibit diverse biological activities, including antioxidant, antibacterial, anticancer, anti-diabetic, anti-inflammatory, anti-bacterial, anti-viral, anti-HIV, anti-acetylcholinestrase, nephroprotective and hepatoprotective activities.