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Published in:

Volume 5 Issue 12
January-2019
eISSN: 2349-5162

Unique Identifier

JETIR1812983

Page Number

590-600

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Title

SYNTHESIS OF NOVEL 1,1'-(ETHANE-1,2- DIYL BIS(4,1-PHENYLENE))BIS(4-SUBSTITUTED-PHENYL-3-CHLOROAZETIDIN-2-ONES)FROM 1,2-DIANILINO ETHANE,THEIR CHARACTERIZATION AND EVALUATION OF THEIR ANTI BACTERIAL ACTIVITY

ISSN

2349-5162

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"SYNTHESIS OF NOVEL 1,1'-(ETHANE-1,2- DIYL BIS(4,1-PHENYLENE))BIS(4-SUBSTITUTED-PHENYL-3-CHLOROAZETIDIN-2-ONES)FROM 1,2-DIANILINO ETHANE,THEIR CHARACTERIZATION AND EVALUATION OF THEIR ANTI BACTERIAL ACTIVITY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.590-600, January-2019, Available :http://www.jetir.org/papers/JETIR1812983.pdf

Abstract

A series of bis azetidinones were synthesized by treating the Schiff bases of 1,2- dianilino ethane(bis-imines)with chloro acetyl chloride in 1,4 dioxan using a catalytic quantity of triethyl amine.These Schiff bases were synthesized using a series of aromatic and hetero cyclic aldehydes and 4,4' diamino bibenzyl in alcohol using catalytic quantity of glacial acetic acid.The structures of these synthesized compounds were confirmed by IR and 1H NMR spectral analysis.All the synthesized compounds were tested for their antimicrobial activity using S.aureus and E.coli and for their antifungal activity using Penicillium citrinum and Fusarium oxysporum.These compounds showed moderate to good antimicrobial activity but no antifungal activity.

Key Words

1,2-dianilino ethane,Bis Azetidinones,antifungal,antibacterials,β lactam

Cite This Article

"SYNTHESIS OF NOVEL 1,1'-(ETHANE-1,2- DIYL BIS(4,1-PHENYLENE))BIS(4-SUBSTITUTED-PHENYL-3-CHLOROAZETIDIN-2-ONES)FROM 1,2-DIANILINO ETHANE,THEIR CHARACTERIZATION AND EVALUATION OF THEIR ANTI BACTERIAL ACTIVITY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp590-600, January-2019, Available at : http://www.jetir.org/papers/JETIR1812983.pdf

Publication Details

Published Paper ID: JETIR1812983
Registration ID: 194251
Published In: Volume 5 | Issue 12 | Year January-2019
DOI (Digital Object Identifier):
Page No: 590-600
ISSN Number: 2349-5162

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Cite This Article

"SYNTHESIS OF NOVEL 1,1'-(ETHANE-1,2- DIYL BIS(4,1-PHENYLENE))BIS(4-SUBSTITUTED-PHENYL-3-CHLOROAZETIDIN-2-ONES)FROM 1,2-DIANILINO ETHANE,THEIR CHARACTERIZATION AND EVALUATION OF THEIR ANTI BACTERIAL ACTIVITY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp590-600, January-2019, Available at : http://www.jetir.org/papers/JETIR1812983.pdf




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