• Sr.T. Jhony Dathees
• S.Vinitha
• J.Vijayalakshmi
• Sr.Sahaya Leenus

Abstract 　　　　The development of nanotechnology interests the researchers for synthesis of nanoparticles with various bio-applications. Research on green production methods for metal oxide nanoparticles is growing with the objective to overcome the potential hazards of these chemicals for a safer environment. The present investigation was made to synthesis copper oxide nanoparticles by using medicinal plants Solanum Nigrum and Solanum Trilobatum. The bio-molecules present in the leaf extract react with copper sulphate, upon reduction at room temperature resulted in the formation of copper oxide nanoparticles. The biosynthesized copper oxide nanoparticles were characterized by using UV-Visible absorption Spectroscopy, Fourier Transform Infrared Spectroscopy (FT-IR), X-ray Diffraction (XRD) and Scanning Electron Microscopy (SEM) techniques. These analytical techniques clearly confirm the formation of copper oxide with monoclinic structure. The antimicrobial assays were demonstrated against some bacterial and fungal growth. The biologically synthesized CuO nanoparticles were found to be effective in controlling the growth of human pathogens Eschercia coli, Klebsiella and Staphylococcus Aureus. The maximum zone of inhibition was found to be more in gram positive bacteria when compared to gram negative bacteria. Our method utilizes an economic, eco-friendly and bio-compatible reducing agent for the synthesis of copper oxide nanoparticles.

Keywords : Solanum nigrum, Solanum trilobatum, UV-VIS, FT-IR, XRD, SEM, E.Coli, Klebsiella, S.aureus, Candida albicans.

"Green Synthesis of Copper Oxide Nanoparticles and their antimicrobial activity", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 1, page no.831-840, January-2020, Available :http://www.jetir.org/papers/JETIR1908915.pdf

"Green Synthesis of Copper Oxide Nanoparticles and their antimicrobial activity", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 1, page no. pp831-840, January-2020, Available at : http://www.jetir.org/papers/JETIR1908915.pdf