UGC Approved Journal no 63975(19)

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Published in:

Volume 7 Issue 2
February-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2002260


Registration ID:
228040

Page Number

392-400

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Title

A STASTISTCAL APPORACH IN DETERMINING THE CHEMICAL AND BIOLOGICAL STUDY OF ANDROGAPHIS PANICULATA

Abstract

Chemical investigation of the dichloromethane extracts of Andrographis paniculata Nees led to the isolation of andrographolide (1), 14-deoxyandrographolide (2), 14-deoxy-12-hydroxyandrographolide (3), a mixture of β-sitosterol (4a) and stigmasterol (4b) in a 3:1 ratio, and chlorophyll a (5) from the leaves; a mixture of 4a and 4b in a 3:2 ratio, 5,2'-dihydroxy-7,8-dimethoxyflavone or skullcapflavone I (6), and a mixture of long chain trans-cinnamate esters (7a) and β-sitosteryl fatty acid esters (7b) from the roots; 4a, monogalactosyl diacylglycerols (8), lupeol (9), and triacylglycerols (10) from the pods; and 2 from the stems. The structures of 1-3 and 6 were elucidated by extensive 1D and 2D NMR spectroscopy, while the structures of 4, 5 and 7-10 were identified by comparison of their NMR data with those reported in the literature. The dichloromethane extracts of the leaves of Andrographis paniculata led to the isolation of neoandrographolide (1), 1,5-dimethyl-1,5-cyclooctadiene (2) and 2-hydroxyethyl benzoate (3), and squalene (4) from the leaves, while the stems yielded 1 and 2. The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy.

Key Words

A STASTISTCAL APPORACH IN DETERMINING THE CHEMICAL AND BIOLOGICAL STUDY OF ANDROGAPHIS PANICULATA

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"A STASTISTCAL APPORACH IN DETERMINING THE CHEMICAL AND BIOLOGICAL STUDY OF ANDROGAPHIS PANICULATA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 2, page no.392-400, February-2020, Available :http://www.jetir.org/papers/JETIR2002260.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"A STASTISTCAL APPORACH IN DETERMINING THE CHEMICAL AND BIOLOGICAL STUDY OF ANDROGAPHIS PANICULATA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp392-400, February-2020, Available at : http://www.jetir.org/papers/JETIR2002260.pdf

Publication Details

Published Paper ID: JETIR2002260
Registration ID: 228040
Published In: Volume 7 | Issue 2 | Year February-2020
DOI (Digital Object Identifier):
Page No: 392-400
Country: -, -, - .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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