• Neha Chauhan (Corresponding Author)
• Pooja Uniyal (First Author)
• Heena
• Sapna Gupta
• Chhaya Singh

The present investigation focused on exploiting the therapeutic potential of Ficus religiosa and Ficus racemosa against selected gram positive and gram negative human pathogens. Significant botanicals of leaves of Ficus religiosa (Chloroform, Ethanol and Methanol) and Ficus racemosa (Petroleum Ether, Chloroform and Methanol) were extracted in solvents of increasing polarity using Cold Masceration technique. Antimicrobial activity of Ficus religiosa and Ficus racemosa leaf extracts was assessed using agar well diffusion method and MIC assay, against gram positive bacteria Bacillus subtilis, Staphylococcus aureus and gram negative bacteria E.coli, Salmonella typhi. The highest ZOI values were obtained against S.aureus at 1mg/100l (21mm) of chloroform extract in case of F.religiosa whereas F.racemosa effectively inhibited S.typhi at 1mg/100l (20mm) of methanol extract. Preliminary phytochemical analysis marked the presence of alkaloids, tannins, saponins, flavonoids as the active bio ingredients in F. religiosa and F. racemosa various solvent extracts. Conclusive evidences on the basis of data generated showed that selected medicinal plant extracts has a potent inhibitory efficiency in treating bacterial infections caused by gram positive and gram negative bacteria in reference.

Keywords: Ficus religiosa, Ficus racemosa, Antimicrobial activity, Phytochemical, Zone of inhibition, Human pathogens.

"PHYTOCHEMISTRY AND ANTIMICROBIAL ACTIVITY OF FICUS RELIGIOSA AND FICUS RACEMOSA VARIOUS SOLVENT LEAF EXTRACTS ON GRAM POSITIVE AND GRAM NEGATIVE BACTERIA.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 3, page no.475-485, March-2020, Available :http://www.jetir.org/papers/JETIR2003076.pdf

"PHYTOCHEMISTRY AND ANTIMICROBIAL ACTIVITY OF FICUS RELIGIOSA AND FICUS RACEMOSA VARIOUS SOLVENT LEAF EXTRACTS ON GRAM POSITIVE AND GRAM NEGATIVE BACTERIA.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp475-485, March-2020, Available at : http://www.jetir.org/papers/JETIR2003076.pdf