UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 7 Issue 5
May-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2005360


Registration ID:
227946

Page Number

345-356

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Title

Nanostructured Lipid carrier: A Novel Approach to enhance Solubility, Bioavailability, Stability and Permeability of Drug.

Abstract

The number of studies describing nanostructured lipid carrier (NLC) based formulation has been increased solubility, bioavailability, and stability of drug and formulation. Both solid lipids and Liquid lipids are used to compose the core matrix of Nanostructured lipid carriers. Nanostructured lipid carrier shows some advantages over traditional drug delivery systems, including increase the solubility and ability to enhance storage stability, improved permeability and bioavailability, reduced adverse effect, prolonged half-life, and tissue-targeted delivery.[61] NLCs have attracted increasing attention in recent years, finally, the Application of NLC and the approach of formulating NLC in a different form are discussed. This article will focus on Nanostructure lipid carriers and the development of NLC formulation, their safety, applications, and especially their ability to improve drug delivery. NLC entrapped drugs to facilitate solubility and stability, and because of its crystalline, amorphous nature. It shows to rapidly dissociate after parenteral drug administration and to result in the superior oral bioavailability of poorly water-soluble drugs. The enhancement in solubility, bioavailability, permeability, and stability of some drugs are reviewed

Key Words

Nanostructured lipid carrier. Solubility, Bioavailability, Permeability, Parentral

Cite This Article

"Nanostructured Lipid carrier: A Novel Approach to enhance Solubility, Bioavailability, Stability and Permeability of Drug.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 5, page no.345-356, May-2020, Available :http://www.jetir.org/papers/JETIR2005360.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Nanostructured Lipid carrier: A Novel Approach to enhance Solubility, Bioavailability, Stability and Permeability of Drug.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 5, page no. pp345-356, May-2020, Available at : http://www.jetir.org/papers/JETIR2005360.pdf

Publication Details

Published Paper ID: JETIR2005360
Registration ID: 227946
Published In: Volume 7 | Issue 5 | Year May-2020
DOI (Digital Object Identifier):
Page No: 345-356
Country: Ahemadnagar, Maharashtra, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


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