UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 7 Issue 5
May-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2005406


Registration ID:
233489

Page Number

663-666

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Title

In-vitro Evaluation of mutagenic and anti-mutagenic effects of Siddha formulation Mathan thailam

Abstract

Many Siddha formulations are used for the treatment of infectious diseases but literature search revealed very less number of scientific studies on mutagenic properties of Siddha formulations. In India the use of traditional herbal remedies plays as alternative medicine, and the effectiveness and harmful properties are based on the previous data. The present study performs the evaluation of the mutagenic and anti-mutagenic effects of the Siddha formulation Mathan thailam. Mathan Thailam contains Datura leaf juice, Coconut oil and Copper sulphate. This commercially available formulation is used for treating various skin diseases in traditional clinical practice in India The drug was screened for mutagenicity and antimutagenicity using the Salmonella mutagenicity assay (Ames test). This study results explains the Genotoxicity of Mathan Thailam will provide information and evidence for additional research. Biological and statistical results are considered for evaluation. This test results reveals that Mathan Thailam not induced any gene mutations in TA 1537, TA 1535, TA 98, TA 100 and TA 102 Salmonella typhimurium tester strains at the test doses 5, 2.5, 1.25, 0.625, 0.312 ml/plate, in the presence and absence of metabolic activation system.

Key Words

Ames test, Mathan Thailam, Siddha formulations, mutagenic and anti-mutagenic tests

Cite This Article

"In-vitro Evaluation of mutagenic and anti-mutagenic effects of Siddha formulation Mathan thailam", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 5, page no.663-666, May 2020, Available :http://www.jetir.org/papers/JETIR2005406.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"In-vitro Evaluation of mutagenic and anti-mutagenic effects of Siddha formulation Mathan thailam", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 5, page no. pp663-666, May 2020, Available at : http://www.jetir.org/papers/JETIR2005406.pdf

Publication Details

Published Paper ID: JETIR2005406
Registration ID: 233489
Published In: Volume 7 | Issue 5 | Year May-2020
DOI (Digital Object Identifier):
Page No: 663-666
Country: Pondicherry, Puducherry, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


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