• Ryan Andrian

Background: The contraception injection is the most widely used contraception including Cyclofem. In practice, synthetic progesterone may cause changes in the menstrual cycle and causes discomfort for the acceptor so the acceptor sometimes chooses to stop using it. This study was a follow-up study of clinical trial research phase III, from the group of acceptors using Gestin F2 and Gestin F3 injections compared to Cyclofem injections that have been done by previous researchers in which he conducted research to develop contraception injection Gestin F2® and Gestin F3®, with the aim to reduce discomfort and ineffective use of contraception injections. Objective: To find out the difference in the cycle and menstrual duration in the use of hormonal contraceptive combination injections every 1 month (Cyclofem), contraception injections every 2 months and contraception injections every 3 months. Methods: This research is a descriptive analytic study with Case Series design. To assess the difference between cyclofem, 2-month hormonal injections and 3-month hormonal injections in changes in the menstrual cycle. Multivariate statistical analysis was performed using the Kruskal Wallis test. Results: This research was conducted on 120 people, divided by 3 gripus with of 40 people in each study group. The mean age in the 1-month injection study group was 30.9 years, the 2-month injection group 33.73 years and in the 3-month injection group with a mean age of 31.98 years. Evaluation of menstrual cycles in the 3 to 12 months appeared throughout the study group, the majority of menstrual cycles are normal with a mean cycle between 28-29 days. While the evaluation of menstrual length was done at the same time, it was found that the majority of menstrual periods were normal with an average of 5 days in all study groups. The p value obtained in the menstrual cycle with all three study groups was 0.387 (p => 0.05) and the p value for the duration of menstruation with all three study groups was 0.755 (p => 0.05). Conclusion: There was no difference between the menstrual cycle and menstrual length in the three study groups.

Menstrual cycle, injection hormonal contraception

"COMPARISON OF CHANGES OF MENSTRUAL CYCLE AS EFFECTS ON THE USE OF HORMONAL CONTRACEPTION IN COMBINATION OF INJECTION IN 1 MONTH, INJECTION IN 2 MONTHS, AND INJECTION IN 3 MONTHS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 7, page no.1246-1255, July-2020, Available :http://www.jetir.org/papers/JETIR2007153.pdf

"COMPARISON OF CHANGES OF MENSTRUAL CYCLE AS EFFECTS ON THE USE OF HORMONAL CONTRACEPTION IN COMBINATION OF INJECTION IN 1 MONTH, INJECTION IN 2 MONTHS, AND INJECTION IN 3 MONTHS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 7, page no. pp1246-1255, July-2020, Available at : http://www.jetir.org/papers/JETIR2007153.pdf