• Mahesh Balkisan Gaikwad
• R.K. DUMBARE
• Narendra Govikar

RP-HPLC for the determination of apremilast tablet dosage form the chromatographic s9999on was carried out UV 1700 detector, utilising C18 column (based on 99.999% ultra high purity silica ) 150 mm ×4.6 mm ,5µm particle size, utilising water methanol, triethylamine, at flow rate 1ml/min within injection vol. 20µl was selected for this study. The sepreation was carried out at a room temperature and the eluentant werw observed by photodiode array detector set a 264nm. The retention time of apremilast obtained was at 3.9 min. thus the propose method for APR was found to be feasible for estimation of APR in pharmaceutical dosage form.

HPLC, Mobile phase ,

"DEVLOPMENT AND VALIDATION OF RP- HPLC METHOD FOR ESTIMATION OF APREMILAST IN TABLET DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 10, page no. 917-931, October-2020, Available :http://www.jetir.org/papers/JETIR2009124.pdf

"DEVLOPMENT AND VALIDATION OF RP- HPLC METHOD FOR ESTIMATION OF APREMILAST IN TABLET DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 10, page no. pp 917-931, October-2020, Available at : http://www.jetir.org/papers/JETIR2009124.pdf