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Published in:

Volume 7 Issue 9
September-2020
eISSN: 2349-5162

Unique Identifier

JETIR2009124

Page Number

917-931

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Title

DEVLOPMENT AND VALIDATION OF RP- HPLC METHOD FOR ESTIMATION OF APREMILAST IN TABLET DOSAGE FORM

ISSN

2349-5162

Cite This Article

"DEVLOPMENT AND VALIDATION OF RP- HPLC METHOD FOR ESTIMATION OF APREMILAST IN TABLET DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 9, page no.917-931, September-2020, Available :http://www.jetir.org/papers/JETIR2009124.pdf

Abstract

RP-HPLC for the determination of apremilast tablet dosage form the chromatographic s9999on was carried out UV 1700 detector, utilising C18 column (based on 99.999% ultra high purity silica ) 150 mm ×4.6 mm ,5µm particle size, utilising water methanol, triethylamine, at flow rate 1ml/min within injection vol. 20µl was selected for this study. The sepreation was carried out at a room temperature and the eluentant werw observed by photodiode array detector set a 264nm. The retention time of apremilast obtained was at 3.9 min. thus the propose method for APR was found to be feasible for estimation of APR in pharmaceutical dosage form.

Key Words

HPLC, Mobile phase ,

Cite This Article

"DEVLOPMENT AND VALIDATION OF RP- HPLC METHOD FOR ESTIMATION OF APREMILAST IN TABLET DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 9, page no. pp917-931, September-2020, Available at : http://www.jetir.org/papers/JETIR2009124.pdf

Publication Details

Published Paper ID: JETIR2009124
Registration ID: 300635
Published In: Volume 7 | Issue 9 | Year September-2020
DOI (Digital Object Identifier):
Page No: 917-931
ISSN Number: 2349-5162

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Cite This Article

"DEVLOPMENT AND VALIDATION OF RP- HPLC METHOD FOR ESTIMATION OF APREMILAST IN TABLET DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 9, page no. pp917-931, September-2020, Available at : http://www.jetir.org/papers/JETIR2009124.pdf




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