JETIREXPLORE- Search Thousands of research papers



Published in:

Volume 7 Issue 11
November-2020
eISSN: 2349-5162

Unique Identifier

JETIR2011043

Page Number

272-279

Share This Article


Title

OVERVIEW ON FLOATING GASTRORETENTIVE DRUG DELIVERY SYSTEMS FOR IMPROVING ORAL BIOAVAILABILITY OF DRUGS

ISSN

2349-5162

Cite This Article

"OVERVIEW ON FLOATING GASTRORETENTIVE DRUG DELIVERY SYSTEMS FOR IMPROVING ORAL BIOAVAILABILITY OF DRUGS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 11, page no.272-279, November-2020, Available :http://www.jetir.org/papers/JETIR2011043.pdf

Abstract

In recent decades, extensive research has been conducted to develop a floating gastroretentive drug delivery (FGRDD).Gastroretentive drug delivery systems are a good example; have emerged to increase the bioavailability and efficacy of drugs with a narrow absorption window in the upper gastrointestinal tract and / or to promote local stomach and duodenal activity. drugs that are locally active in the stomach and upper intestine because FGRDD allows the drug to stay in the stomach for a longer period of time. these types of systems have both advantages and disadvantages. Intraindividual and differences in gastric physiology are obstacles to the development of efficient FGRDD. These include gastric pH and gastric motility, which have a significant impact on gastric retention time. Some of these obstacles can be overcome by developing a new floating drug delivery system. In this review, research and development of speed-controlled floating release systems overcoming physiological adversities, such as short gastric residence times (GRT) and unpredictable gastric emptying times (GET).

Key Words

Floating gastroretentive drug delivery, gastric motility, gastroretentive narrow absorption window, controlled drug release, gastro retentive system, gastric retention time

Cite This Article

"OVERVIEW ON FLOATING GASTRORETENTIVE DRUG DELIVERY SYSTEMS FOR IMPROVING ORAL BIOAVAILABILITY OF DRUGS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 11, page no. pp272-279, November-2020, Available at : http://www.jetir.org/papers/JETIR2011043.pdf

Publication Details

Published Paper ID: JETIR2011043
Registration ID: 303225
Published In: Volume 7 | Issue 11 | Year November-2020
DOI (Digital Object Identifier):
Page No: 272-279
ISSN Number: 2349-5162

Download Paper

Preview Article

Download Paper




Cite This Article

"OVERVIEW ON FLOATING GASTRORETENTIVE DRUG DELIVERY SYSTEMS FOR IMPROVING ORAL BIOAVAILABILITY OF DRUGS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 11, page no. pp272-279, November-2020, Available at : http://www.jetir.org/papers/JETIR2011043.pdf




Preview This Article


Downlaod

Click here for Article Preview