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Published in:

Volume 8 Issue 2
February-2021
eISSN: 2349-5162

Unique Identifier

JETIR2102084

Page Number

710-724

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Title

Clinicoserological diagnosis of Dengue fever.

ISSN

2349-5162

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"Clinicoserological diagnosis of Dengue fever.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 2, page no.710-724, February-2021, Available :http://www.jetir.org/papers/JETIR2102084.pdf

Abstract

Introduction- Dengue is an endemic vector borne viral disease which is transmitted by bite if Aedes mosquito. Diagnosis of Dengue by viral isolation is cumbersome and is not practiced so, ELISA and rapid immunochromatography are mainstay of diagnosis. Aims and objectives- 1. To assess the occurrence of seropositivity in clinically suspected Dengue patients at Tertiary care hospital. 2. To determine the occurrence of primary and secondary Dengue infection amongst clinically suspected cases of Dengue. 3. To evaluate utility of serodiagnosis and correlate results with clinical and laboratory profile. 4. To evaluate the efficacy of NS1 Antigen (Ag) assay as an early marker for Dengue virus infection. 5. To assess the seasonal pattern of Dengue over the study period at Tertiary care hospital. Material and methods- Blood samples were taken from 350 clinically suspected Dengue cases. Panbio ELISA kits were used for IgM, IgG antibodies and NS1 antigen testing. J Mitra kits were used for Rapid immunochromatographic testing. Results- 35.43% were serologically positive for Dengue. 16-30 years was most commonly affected age group. Males were more affected than females.Most of the cases were seen in November. Headache was most common symptom. Platelet count was <1,00,000/µL in 73.39% cases. Maximum numbers of cases were of Dengue with warning signs i.e. 54.03%.ELISA was more sensitive than Rapid test. Secondary Dengue was more common than primary Dengue. NS1 proved an important tool for diagnosis of early dengue infection. Conclusion- Correlation of clinical symptoms is necessary along with laboratory tests.

Key Words

Aedes, Dengue, ELISA, NS1, Platelet, Secondary Dengue

Cite This Article

"Clinicoserological diagnosis of Dengue fever.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 2, page no. pp710-724, February-2021, Available at : http://www.jetir.org/papers/JETIR2102084.pdf

Publication Details

Published Paper ID: JETIR2102084
Registration ID: 305585
Published In: Volume 8 | Issue 2 | Year February-2021
DOI (Digital Object Identifier):
Page No: 710-724
ISSN Number: 2349-5162

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Cite This Article

"Clinicoserological diagnosis of Dengue fever.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 2, page no. pp710-724, February-2021, Available at : http://www.jetir.org/papers/JETIR2102084.pdf




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