• Soham Samajpaty

Although widely neglected in the world of medicine and research and development programs, enzyme hemaglutanin esterase is a domain of utmost importance in Virology and developmental biology of virus. Without this enzyme many virus are functionally cripple which amplifies its importance manifold. The enzyme facilitates binding of a huge range of virus to its host receptor, change in kinetics of this grossly affects such function. The enzyme is widely found in influenza C virus, toroviridae and coronaviridae groups. Primarily consisting of three functional roles; receptor binding activity, receptor hydrolysis activity and membrane fusion activity, it’s an indispensable part of a functional virus. The enzyme has wide-scale implications. It has a very complex structure, varying from one virus to another. Not enough light has been ushered on the chemistry of this enzyme but available literature indicates the complex chemical functioning of it as well. It’s presence in wide range of viruses affecting animal worlds including humans and wild species alike, makes it a necessary topic for intense discourse of research. Structural complexity of each domain of HE is such that many could not have been resolved by spectroscopy as well. In brief, enzyme Hemagglutanin Esterase is the “energy shutting system” which enables virus to infect its host species and ensures its sustainability.

Heemagglutanin Esterase, Coronaviridae, COVID19, virology, developmental biology

"Review of Enzyme Hemagglutanin Esterase", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 3, page no.1967-1971, March-2021, Available :http://www.jetir.org/papers/JETIR2103243.pdf

"Review of Enzyme Hemagglutanin Esterase", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 3, page no. pp1967-1971, March-2021, Available at : http://www.jetir.org/papers/JETIR2103243.pdf