• Murshida Karim

In this article, we have reported the synthesis of four different 2-aryl benzothiazoles namely 2-Phenyl-1, 3-benzothiazole, 2-(4-Chlorophenyl)-1, 3-benzothiazole, 2-(4-Bromophenyl)-1, 3-benzothiazole and 2-(3-Nitrophenyl)-1, 3-benzothiazole by using grinding method with minimum amount of the solvent. All the synthesised compounds were characterized by IR, 1H- NMR and melting point analysis. We have also studied the antibacterial activity of these four prepared compounds against two gram negative bacterial strains namely Klebsiella sp. and Salmonella sp by Disk diffusion method. Amongst these four 2-aryl benzothiazoles, 2-(4-Chlorophenyl)-1, 3-benzothiazole have distinctive inhibitory property against Klebsiella sp. and 2-(4-bromophenyl)-1, 3-benzothiazole have inhibitory activity against Salmonella sp. for higher concentrations only.

2-Aryl benzothiazoles, Klebsiella sp., Salmonella sp., Disk diffusion method, Antibacterial

"Synthesis, Characterisation and Antibacterial activity of 2-Aryl Benzothiazoles", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.646-653, May 2019, Available :http://www.jetir.org/papers/JETIRCU06121.pdf

"Synthesis, Characterisation and Antibacterial activity of 2-Aryl Benzothiazoles", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp646-653, May 2019, Available at : http://www.jetir.org/papers/JETIRCU06121.pdf