JETIREXPLORE- Search Thousands of research papers



Published in:

Volume 7 Issue 2
February-2020
eISSN: 2349-5162

Unique Identifier

JETIRDI06027

Page Number

139-145

Share This Article


Title

Quinoxaline based nanoprobe for selective detection of Adenine in aqueous medium: Application to Biological sample

ISSN

2349-5162

Cite This Article

"Quinoxaline based nanoprobe for selective detection of Adenine in aqueous medium: Application to Biological sample", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 2, page no.139-145, February-2020, Available :http://www.jetir.org/papers/JETIRDI06027.pdf

Abstract

Quinoxaline based derivative 2,3-diphenyl quinoxaline (DPQ) was synthesized followed by spectral characterization. The aqueous suspension of DPQ nanoparticles (DPQNPs) were prepared by reprecipitation method. The average particle size of NPs obtained from Dynamic Light Scattering (DLS) examination is 52 nm. While field emission scanning electron microscopy (FE-SEM) analysis of air-dried film of aqueous suspension of NPs showed spherical morphology. Aggregation Induced Enhanced Emission (AIEE) of suspension of DPQNPs found red shifted when compared with emission arising from DPQ in THF solution. The zeta potential value of NPs is -23.3 mV indicates stability and ability of DPQNPs to interact with oppositely charged analyte molecules. The recognition test based on fluorescence shows quenching of fluorescence arising from DPQNPs suspension by addition of adenine (AD) solution. Effect of interfering substances on quenching capacity of adenine examined in presence of other ions indicated that adenine response is of high order while other ions responded negligibly. The possible mechanism of fluorescence quenching of NPs upon interaction with Adenine molecule was discussed on the basis of surface adsorption and ground state complex formation between them through H-bonding. Further the proposed fluorescence quenching method was successfully applied for the detection of adenine in serum sample by standard addition method.

Key Words

Quinoxaline based nanoprobe for selective detection of Adenine in aqueous medium: Application to Biological sample

Cite This Article

"Quinoxaline based nanoprobe for selective detection of Adenine in aqueous medium: Application to Biological sample", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp139-145, February-2020, Available at : http://www.jetir.org/papers/JETIRDI06027.pdf

Publication Details

Published Paper ID: JETIRDI06027
Registration ID: 227543
Published In: Volume 7 | Issue 2 | Year February-2020
DOI (Digital Object Identifier):
Page No: 139-145
ISSN Number: 2349-5162

Download Paper

Preview Article

Download Paper




Cite This Article

"Quinoxaline based nanoprobe for selective detection of Adenine in aqueous medium: Application to Biological sample", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp139-145, February-2020, Available at : http://www.jetir.org/papers/JETIRDI06027.pdf




Preview This Article


Downlaod

Click here for Article Preview