• Mitali B Ghormade

Target based or structural based drug designing is the rapidly growing area. The explosion of genomic, proteomic and structural information has provided hundreds of new targets and opportunity to find new drug lead components. Based on burgeoning structural data of Burkholderia pseudomallei. I focused on tomato disease, Burkholderia pseudomallei also known as Pseudomonas pseudomallei) is a Gram- negative, bipolar, aerobic, motile rod-shaped bacterium. It infects human and animals and cause the disease Melioidosis , it also infect plants. In this study I have taken 592 protein sequences from NCBI (National Centre of Biotechnological Information) protein database for which protein structure is available at PDB Database. From this study we have selected 4 druggable targets & 4 virulence protein sequences using Tid tool out of detected virulence protein we have choose 4bko protein as target.

Target identification & molecular docking of Burkholderia pseudomallei

"Target identification & molecular docking of Burkholderia pseudomallei", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 2, page no.252-259, February-2020, Available :http://www.jetir.org/papers/JETIRDI06049.pdf

"Target identification & molecular docking of Burkholderia pseudomallei", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp252-259, February-2020, Available at : http://www.jetir.org/papers/JETIRDI06049.pdf