• V A Sadafale
• P R Mandlik
• S.S.wagh

Complexes of Cr(III), Mn(III), Fe(III) and VO(IV) with Schiff base derived from 2,4-dihydroxyacetophenone and sulphapyridine were synthesized and characterized using elemental analysis, molar conductance, magnetic susceptibility measurements, spectral studies (IR, 1H NMR, UV- Visible) mass and TGA. Elemental analysis of the complexes suggested 1:2 metal:ligand stoichiometry in case of VO(IV) complex whereas 1:1 metal:ligand ratio for Cr(III), Mn(III) and Fe(III) complexes. The molar conductance measurements reveal the non-electrolytic nature of all the complexes. IR spectra of the compounds show monobasic bidentate (ON) nature of the ligand, coordinating mainly through hydroxyl oxygen and azomethine nitrogen. The electronic spectral data supported octahedral geometry for Cr(III), Mn(III) and Fe(III) complexes while square pyramindal for VO(IV) complex. Thermogravimetric analysis shows that the complexes are thermally more stable than that of the ligand. Kinetic parameters were calculated by using Freeman-Carroll and Sharp-Wentworth methods and results are comparable. All the compounds have been tested in vitro to evaluate their antimicrobial activity against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Klebsella pneumoniae using well-diffusion method.

2,4-dihydroxybenzophenone, sulphapyridine, well-diffusion.

"“Cr(III), Mn(III), Fe(III) and VO(IV) complexes of 2,4-dihydroxyacetophenone and sulphapyridine.”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 2, page no.369-374, February-2020, Available :http://www.jetir.org/papers/JETIRDI06072.pdf

"“Cr(III), Mn(III), Fe(III) and VO(IV) complexes of 2,4-dihydroxyacetophenone and sulphapyridine.”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp369-374, February-2020, Available at : http://www.jetir.org/papers/JETIRDI06072.pdf