• Gopinath S. Khansole
• Sunil S. Choudhare
• Swapnil S.Nawhate
• Vijay N. Bhosale

A simple, most efficient and green procedure has been developed for the synthesis of pyrimido [4,5-d] [1,3,4] thiadiazolo [3,2-a] pyrimidinedione derivatives from one-pot three component condensation reactions of barbituric acid, substituted aromatic aldehydes, and 2-amino 5-(4-chlorophenyl)-1,3,4-thiadiazole using 1-Butyl-3-methyl Imidazolium Chloride [BMIM]Cl as a green catalyst in ethanol-water. The newly synthesized compounds evaluated by their spectral techniques and screened for their Antimicrobial activity.

Barbituric acid, Aromatic Aldehyde, 2-amino 5-(4-chlorophenyl)-1,3,4-thiadiazole, MCRs, [BMIM]Cl

"SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF PYRIMIDO [4,5-d] [1,3,4] THIADIAZOLO[3,2-a]PYRIMIDINEDIONE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 3, page no.4-8, March-2020, Available :http://www.jetir.org/papers/JETIRDN06002.pdf

"SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF PYRIMIDO [4,5-d] [1,3,4] THIADIAZOLO[3,2-a]PYRIMIDINEDIONE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp4-8, March-2020, Available at : http://www.jetir.org/papers/JETIRDN06002.pdf