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Published in:

Volume 7 Issue 3
March-2020
eISSN: 2349-5162

Unique Identifier

JETIRDN06020

Page Number

97-105

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Title

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING ASSAY METHOD FOR SIMULTANEOUS ESTIMATION OF METFORMIN AND TENELIGLIPTIN HYDROBROIDE COMBINED DOSAGE FORM

ISSN

2349-5162

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"DEVELOPMENT AND VALIDATION OF STABILITY INDICATING ASSAY METHOD FOR SIMULTANEOUS ESTIMATION OF METFORMIN AND TENELIGLIPTIN HYDROBROIDE COMBINED DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 3, page no.97-105, March-2020, Available :http://www.jetir.org/papers/JETIRDN06020.pdf

Abstract

Simple, precise and reproducible UV spectrophotometric methods, simultaneous Equation analysis method, have been developed and validated for the simultaneous estimation of Teneligliptin Hydrobromide and Metformin Hydrochloride used as anti dibetic drugs available in Tablet dosage form. In UV spectrophotometric method, the solutions of Teneligliptin HBr and Metformin HCl were prepared in water. The methods are based on the measurement of absorbance of Teneligliptin Hydrobromide and Metformin Hydrochloride at 243 nm and 233 nm respectively. These methods obeyed Beer's law in the concentration range of 10-60 μg /ml for Teneligliptin HBr and 2-12 μg /ml for Metformin HCl. The results of analysis have been validated statistically and recovery studies confirmed the accuracy of the proposed methods. These methods were successfully applied to the determination of these drugs in pharmaceutical dosage forms.

Key Words

Teneligliptin Hydrobromide and Metformin Hydrochloride UV Spectrophotometry

Cite This Article

"DEVELOPMENT AND VALIDATION OF STABILITY INDICATING ASSAY METHOD FOR SIMULTANEOUS ESTIMATION OF METFORMIN AND TENELIGLIPTIN HYDROBROIDE COMBINED DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp97-105, March-2020, Available at : http://www.jetir.org/papers/JETIRDN06020.pdf

Publication Details

Published Paper ID: JETIRDN06020
Registration ID: 229523
Published In: Volume 7 | Issue 3 | Year March-2020
DOI (Digital Object Identifier):
Page No: 97-105
ISSN Number: 2349-5162

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Cite This Article

"DEVELOPMENT AND VALIDATION OF STABILITY INDICATING ASSAY METHOD FOR SIMULTANEOUS ESTIMATION OF METFORMIN AND TENELIGLIPTIN HYDROBROIDE COMBINED DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp97-105, March-2020, Available at : http://www.jetir.org/papers/JETIRDN06020.pdf




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