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Published in:

Volume 7 Issue 3
March-2020
eISSN: 2349-5162

Unique Identifier

JETIRDN06025

Page Number

125-127

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Title

DIVERGENT AND CONCISE TOTAL SYNTHESES OF DIHYDROCHALCONES: TACCABULIN A, TACCABULIN D AND TACCABULIN E

ISSN

2349-5162

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"DIVERGENT AND CONCISE TOTAL SYNTHESES OF DIHYDROCHALCONES: TACCABULIN A, TACCABULIN D AND TACCABULIN E", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 3, page no.125-127, March-2020, Available :http://www.jetir.org/papers/JETIRDN06025.pdf

Abstract

Dihydrochalcones are the compounds possessing various interesting biologically activities. Herein, we report the concise and divergent total syntheses of three naturally occurring dihydrochalcones from readily available starting materials. The divergent strategy is based around manipulation of a common chalcone scaffold and features application of Grignard Reaction followed by oxidation for synthesising ketones. This is the first reported total synthesis of Taccabulin D.Concise and flexible route should be readily amenable to future analogue generation. Furthermore, this work provides an illustration of the utility of divergent synthesis for the convenient and step-economical preparation of natural product libraries of various dehydrochalcones.

Key Words

Component,formatting,style,styling,insert.

Cite This Article

"DIVERGENT AND CONCISE TOTAL SYNTHESES OF DIHYDROCHALCONES: TACCABULIN A, TACCABULIN D AND TACCABULIN E", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp125-127, March-2020, Available at : http://www.jetir.org/papers/JETIRDN06025.pdf

Publication Details

Published Paper ID: JETIRDN06025
Registration ID: 229517
Published In: Volume 7 | Issue 3 | Year March-2020
DOI (Digital Object Identifier):
Page No: 125-127
ISSN Number: 2349-5162

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Cite This Article

"DIVERGENT AND CONCISE TOTAL SYNTHESES OF DIHYDROCHALCONES: TACCABULIN A, TACCABULIN D AND TACCABULIN E", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp125-127, March-2020, Available at : http://www.jetir.org/papers/JETIRDN06025.pdf




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