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Published in:

Volume 7 Issue 3
March-2020
eISSN: 2349-5162

Unique Identifier

JETIRDN06050

Page Number

214-218

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Title

EQUILIBRIUM STUDIES IN TERNARY COMPLEXES OF METFORMIN- CHROMIUM (III) AND AMINO ACIDS pH METRICALLY

ISSN

2349-5162

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"EQUILIBRIUM STUDIES IN TERNARY COMPLEXES OF METFORMIN- CHROMIUM (III) AND AMINO ACIDS pH METRICALLY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 3, page no.214-218, March-2020, Available :http://www.jetir.org/papers/JETIRDN06050.pdf

Abstract

The present study describes the formation of the Chromium [Cr3+] complexes of Metformin. The properties of the complexes were investigated by measuring the pH values. This is of special interest, owing to their enhanced biological activities. A stability constant of the Ternary complexes formed between the Chromium metal and the anti-diabetic drug Metformin with some biologically important amino acids has been studied using PH Meter at constant ionic strength of 0.1 N NaClO4 . A Chromium (III) complex has been characterized while it’s Binary Studies, this and further the interaction of binary complexes with the important amino acids in the ternary equilibrium. The stability constants of ternary systems as shown by the experimental data. The results showed that the Chromium complexes were formed with the Metformin ligand; thereby, this complex clearly shows a positive synergistic effect. Furthermore, the ternary Chromium complex has been found to show low stability constant values indicating less stability of the ternary complexes than that of the binary complexes.

Key Words

Stability Constants, Ternary Complex, Metformin, Chromium (III)

Cite This Article

"EQUILIBRIUM STUDIES IN TERNARY COMPLEXES OF METFORMIN- CHROMIUM (III) AND AMINO ACIDS pH METRICALLY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp214-218, March-2020, Available at : http://www.jetir.org/papers/JETIRDN06050.pdf

Publication Details

Published Paper ID: JETIRDN06050
Registration ID: 229489
Published In: Volume 7 | Issue 3 | Year March-2020
DOI (Digital Object Identifier):
Page No: 214-218
ISSN Number: 2349-5162

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Cite This Article

"EQUILIBRIUM STUDIES IN TERNARY COMPLEXES OF METFORMIN- CHROMIUM (III) AND AMINO ACIDS pH METRICALLY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp214-218, March-2020, Available at : http://www.jetir.org/papers/JETIRDN06050.pdf




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