• Chetna Rai
• Saurabh Saxena

Hepatitis B and C are one of the major reasons of mortality among the patients of chronic liver disorders. According to WHO, >500 million people are infected worldwide with either hepatitis B virus (HBV) or hepatitis C virus (HCV), out of which, 1 million deaths occur every year. Due to a shared parenteral route of transmission, the HBV and HCV co-infection a common phenomenon. The association between HBV and HCV in coinfected individuals is multifaceted, and viral interference has been well described. It is generally observed that HBV replication is inhibited by HCV in the case of dual infection. The patients suffering from HBVHCV co-infection have more severe liver pathophysiology as compared to mono-infection of either of these viruses. These patients have higher chances of developing liver cirrhosis and hepatocellular carcinoma. Therefore, a thorough serological and virological examination is required before the onset of antiviral therapy. The age, gender and regional distribution of patients have a great impact on acquiring the disorder. Males have more chances of acquiring HBV and HCV infection than females. People residing in rural areas are more vulnerable to the infections than urban people. Both the infections have been found common among the patients of more than 40 years of age. Further, PWID (persons who inject drugs) are always at higher risk of HCV infections due to the usage of shared syringes. Current review focuses on the historical, epidemiological and demographic profile of HCV and HBV infections.

Hepatitis B, hepatitis C, co-infection, drug abusers, epidemiology

"Co-Infection of Hepatitis B and Hepatitis C Virus: An Epidemiological and Demographic Profile", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 11, page no.909-914, November 2018, Available :http://www.jetir.org/papers/JETIRDS06136.pdf

"Co-Infection of Hepatitis B and Hepatitis C Virus: An Epidemiological and Demographic Profile", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 11, page no. pp909-914, November 2018, Available at : http://www.jetir.org/papers/JETIRDS06136.pdf