UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
Call for Paper
Volume 11 | Issue 3 | March 2024

JETIREXPLORE- Search Thousands of research papers



WhatsApp Contact
Click Here

Published in:

Volume 6 Issue 1
January-2019
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

7.95 impact factor calculated by Google scholar

Unique Identifier

Published Paper ID:
JETIRDY06209


Registration ID:
233187

Page Number

1290-1297

Share This Article


Jetir RMS

Title

Genetic polymorphism in CYP11B2 gene associated with hypertension in north Indian population

Abstract

This study was carried on genetic polymorphism of CYP11B2 gene related to hypertension in north Indian population from Punjab region. Hypertension is associated with cardiovascular and kidney diseases. It is mainly caused by high blood pressure which exerts pressure on heart and in arteries which may cause heart failure in severe cases. High dietary intake of sodium is one of the main causative agents for high blood pressure. In adults, alcohol consumption is also associated with hypertension. Previous studies have shown that polymorphism in CYP11B2 gene is associated with hypertension. This gene codes for an enzyme known as Aldosterone synthase which is present in adrenal gland of kidney. Aldosterone synthase is involved in the formation and breakdown of various molecules within the cell. However, the exact mechanism and its association with physiological parameters are lacking. In this study we have compared the genetic polymorphism -344C/T variation and hypertension by PCR-RFLP technique. The study showed that there was significant association between lifestyle and hypertension.

Key Words

CYP11B2, hypertension, cardiovascular diseases, RFLP, genetic polymorphism.

Cite This Article

"Genetic polymorphism in CYP11B2 gene associated with hypertension in north Indian population", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 1, page no.1290-1297, January 2019, Available :http://www.jetir.org/papers/JETIRDY06209.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Genetic polymorphism in CYP11B2 gene associated with hypertension in north Indian population", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 1, page no. pp1290-1297, January 2019, Available at : http://www.jetir.org/papers/JETIRDY06209.pdf

Publication Details

Published Paper ID: JETIRDY06209
Registration ID: 233187
Published In: Volume 6 | Issue 1 | Year January-2019
DOI (Digital Object Identifier):
Page No: 1290-1297
Country: -, -, - .
Area: Other
ISSN Number: 2349-5162
Publisher: IJ Publication


Preview This Article


Downlaod

Click here for Article Preview

Download PDF

Downloads

0003049

Print This Page

Current Call For Paper

Jetir RMS