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Published in:

Volume 5 Issue 12
December-2018
eISSN: 2349-5162

Unique Identifier

JETIREC06082

Page Number

701-710

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Title

Synthesis, Characterization And Biological Activity Of Copper (I) And Silver (I) Complexes Of Thiosemicarbazone Having Heterocyclic Ring

ISSN

2349-5162

Cite This Article

"Synthesis, Characterization And Biological Activity Of Copper (I) And Silver (I) Complexes Of Thiosemicarbazone Having Heterocyclic Ring", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.701-710, December 2018, Available :http://www.jetir.org/papers/JETIREC06082.pdf

Abstract

Reaction of 2-imidazolecarboxyaldehyde thiosemicarbazone (H1L), 2- imidazolecarboxyaldehyde-N-methyl thiosemicarbazone (H2L) and 2-imidazolecarboxyaldehyde-N-phenyl thiosemicarbazone (H3L) with copper(I) and silver(I) halides and triphenylphosphine yielded complexes of stiochiometry, [MX(HL)(Ph3P)2] (1-15). IR spectrum suggested that thio- ligands are binding to metal centre as neutral form thus coordinating via thione sulfur. The expected geometry for complexes is tetrahedral. Thiosemicarbazones and complexes 1-15 were tested for their antibacterial activities. Only complex [CuCl(H2L)(PPh3)2] 6 has shown antibacterial activity in the range 500 ppm (0.66 mm) and 1000 ppm (2.66 mm). Other compounds were found to be inactive.

Key Words

Thiosemicarbazone, 2-imidazolecarboxyaldehyde thiosemicarbazone, copper(I) halides, silver(I) halides, antibacterial activity, NMR spectra

Cite This Article

"Synthesis, Characterization And Biological Activity Of Copper (I) And Silver (I) Complexes Of Thiosemicarbazone Having Heterocyclic Ring", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp701-710, December 2018, Available at : http://www.jetir.org/papers/JETIREC06082.pdf

Publication Details

Published Paper ID: JETIREC06082
Registration ID: 233532
Published In: Volume 5 | Issue 12 | Year December-2018
DOI (Digital Object Identifier):
Page No: 701-710
ISSN Number: 2349-5162

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Cite This Article

"Synthesis, Characterization And Biological Activity Of Copper (I) And Silver (I) Complexes Of Thiosemicarbazone Having Heterocyclic Ring", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp701-710, December 2018, Available at : http://www.jetir.org/papers/JETIREC06082.pdf




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