• Manju
• Rekha Sharma

Reaction of 2-imidazolecarboxyaldehyde thiosemicarbazone (H1L), 2- imidazolecarboxyaldehyde-N-methyl thiosemicarbazone (H2L) and 2-imidazolecarboxyaldehyde-N-phenyl thiosemicarbazone (H3L) with copper(I) and silver(I) halides and triphenylphosphine yielded complexes of stiochiometry, [MX(HL)(Ph3P)2] (1-15). IR spectrum suggested that thio- ligands are binding to metal centre as neutral form thus coordinating via thione sulfur. The expected geometry for complexes is tetrahedral. Thiosemicarbazones and complexes 1-15 were tested for their antibacterial activities. Only complex [CuCl(H2L)(PPh3)2] 6 has shown antibacterial activity in the range 500 ppm (0.66 mm) and 1000 ppm (2.66 mm). Other compounds were found to be inactive.

Thiosemicarbazone, 2-imidazolecarboxyaldehyde thiosemicarbazone, copper(I) halides, silver(I) halides, antibacterial activity, NMR spectra

"Synthesis, Characterization And Biological Activity Of Copper (I) And Silver (I) Complexes Of Thiosemicarbazone Having Heterocyclic Ring", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.701-710, December 2018, Available :http://www.jetir.org/papers/JETIREC06082.pdf

"Synthesis, Characterization And Biological Activity Of Copper (I) And Silver (I) Complexes Of Thiosemicarbazone Having Heterocyclic Ring", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp701-710, December 2018, Available at : http://www.jetir.org/papers/JETIREC06082.pdf