UGC Approved Journal no 63975

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 1 Issue 4
September-2014
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1701400


Registration ID:
303174

Page Number

2478-2480

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Title

GENOTOXIC EFFECT OF DISTILLERY EFFLUENT IN MITOTIC CHROMOSOME OF MICE (MUS MUSCULUS)

Authors

Abstract

Among 300 abnormal metaphase cells the total frequency of abnormalities 18(6.00± 1.37) 24(8.00 ± 1.56) and 32(10.66 ± 1.78) were found. It exhibits that the effect do effluent is dose dependent. C-mitosis, stickness and clumping were common among gross type, while acentric fragment, minute fragment, chromatid break and chromatid gaps were more common among individual type of abnormalities.The individual type of damage were prominent than gross type. This might be due to the formation of electrophilic radicals/ions during the metabolization of mutagens that attack the nucleophilic site of DNA leading to structural changes in chromosome. Effluent probably cause and increase formation of base analogue to act as a mutagen that induce chromosomal abnormalities.

Key Words

Mice, Effluent, Chromosome Anomalies, Bone marrow.

Cite This Article

"GENOTOXIC EFFECT OF DISTILLERY EFFLUENT IN MITOTIC CHROMOSOME OF MICE (MUS MUSCULUS)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.1, Issue 4, page no.2478-2480, September-2014, Available :http://www.jetir.org/papers/JETIR1701400.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"GENOTOXIC EFFECT OF DISTILLERY EFFLUENT IN MITOTIC CHROMOSOME OF MICE (MUS MUSCULUS)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.1, Issue 4, page no. pp2478-2480, September-2014, Available at : http://www.jetir.org/papers/JETIR1701400.pdf

Publication Details

Published Paper ID: JETIR1701400
Registration ID: 303174
Published In: Volume 1 | Issue 4 | Year September-2014
DOI (Digital Object Identifier):
Page No: 2478-2480
Country: Muzaffarpur, Bihar, India .
Area: Physics
ISSN Number: 2349-5162
Publisher: IJ Publication


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