UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
Call for Paper
Volume 11 | Issue 3 | March 2024

JETIREXPLORE- Search Thousands of research papers



WhatsApp Contact
Click Here

Published in:

Volume 5 Issue 8
August-2018
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

7.95 impact factor calculated by Google scholar

Unique Identifier

Published Paper ID:
JETIR1808822


Registration ID:
185241

Page Number

463-471

Share This Article


Jetir RMS

Title

Formulation and Evaluation of Orodispersible tablet of Montelukast sodium and Desloratadine

Abstract

The present study deals with the formulation and evaluation of orally disintegrating drug delivery system using Montelukast sodium along with Desloratadine for the treatment of allergic rhinitis, urticaria. The tablets were prepared using Direct compression technique using Pearlitol as filler, Sucralose as sweetner, Kyron T314 and Crospovidone XL10 as superdisintegrant. Optimization of Kyron T314 was done so as to achieve disintegration within 30 seconds. The formulated formulations were subjected to various evaluation parameters including wetting time, disintegration time, content uniformity and spectrophotometric simultaneous estimation. The in-vitro dissolution studies were performed by USP II type dissolution apparatus in 900 ml of 0.1N HCl medium for Desloratadine and 0.5%SLS for Montelukast sodium at 50 rpm and 37±0.5oC and was compared with the reference market formulation (Mondeslor).

Key Words

ODT, Disintegration time, Dissolution studies, Superdisintegrants

Cite This Article

"Formulation and Evaluation of Orodispersible tablet of Montelukast sodium and Desloratadine", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 8, page no.463-471, August-2018, Available :http://www.jetir.org/papers/JETIR1808822.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Formulation and Evaluation of Orodispersible tablet of Montelukast sodium and Desloratadine", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 8, page no. pp463-471, August-2018, Available at : http://www.jetir.org/papers/JETIR1808822.pdf

Publication Details

Published Paper ID: JETIR1808822
Registration ID: 185241
Published In: Volume 5 | Issue 8 | Year August-2018
DOI (Digital Object Identifier):
Page No: 463-471
Country: Dehradun, Uttarakhand, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


Preview This Article


Downlaod

Click here for Article Preview

Download PDF

Downloads

0002976

Print This Page

Current Call For Paper

Jetir RMS