• Sheetla Prasad

In the study of molecular cell biology, fluorescent biosensors are increasingly needed to detect the true occurrences of physiologically relevant chemicals in live cells. Recent developments in fluorescence biosensors have contributed much to clarifying not only the functions of the individual biomolecules, but also the intracellular dynamics between these molecules. However, fluorescent biosensors' rational design methodologies are not as advanced as they are. An unquenchable yearning for a more universal and adaptable strategy is still an enticing alternative, a so-called modular strategy, which allows easy fabrication of biosensors with custom features by a simple coupling of a receiver and a signal transducer. This review describes progress in fluorescent biomass sensor design strategies, such as autofluorescent protein based biosensors, protein-based biosensors that have covalently been modified with synthetic fluorophorese, and signalling aptamers, and illustrates how a certain receptor has been converted into a fluorescent bio-sensor. In addition, we will highlight the relevance of the modular sensor design concept.

Biosensors, Review, Fabrication

"A Detailed Review on Biosensors", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 9, page no.911-916, September-2018, Available :http://www.jetir.org/papers/JETIR1809927.pdf

"A Detailed Review on Biosensors", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 9, page no. pp911-916, September-2018, Available at : http://www.jetir.org/papers/JETIR1809927.pdf