• C.Kumalasari
• M.Rusda
• ER.Sidabutar
• E.Ardiansyah
• RY.Simanjuntak

The aim of this research were to determine differences in HE4 urine levels in women with ovarian cyst and normal ovary. This research is a comparative analytic, using case control design. This research was conducted in RSUP H. Adam Malik Medan, dr. Pirngadi Medan and the networking hospitals of the Department of Obstetrics and Gynecology of Faculty of Medicine University of North Sumatera from September 2017 to February 2018. The sample is ovarian cyst patients which met the inclusion and exclusion criteria, compared to control group which are women with normal ovary. The mean rank of HE4 level of ovarian cyst patient is 56,35, with the median of 76,41, and min-max 42,40-92,80. Meanwhile in patient with normal ovary, the mean rank of urine HE4 is 24,64, with the median of 49,11, and min-max 30-69. With Mann-Whitney test, p value is 0,000 (p<0,05), showing a significant differences. The mean urine HE4 levels of ovarian cyst is significantly higher than that of in normal ovary.

Urine HE4, Benign epithelial ovarian tumor, Malignant epithelial ovarian tumor

"The Difference Between He4 Expression in Urine of Women with Ovarian Cyst and Women with Normal Ovary", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 10, page no.578-584, October-2018, Available :http://www.jetir.org/papers/JETIR1810870.pdf

"The Difference Between He4 Expression in Urine of Women with Ovarian Cyst and Women with Normal Ovary", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 10, page no. pp578-584, October-2018, Available at : http://www.jetir.org/papers/JETIR1810870.pdf