• KULWANT SINGH
• Dr. SYED SAHAB AHMAD

Cancer is a disease that affects the human population worldwide. New medicines to treat and prevent this life-threatening condition are always in demand. Natural-derived substances are attracting scientific and academic attention since they are thought to have fewer hazardous side effects than conventional therapies like chemotherapy. The effects of plant extracts on human tumour cells (MCF-7, HepG2, HCT116, HeLa, HL-60, and HaCaT) have been investigated in this paper. Crocus sativus (stigma, flowers, leaves, and corms), Juno bucharica (leaves), Gladiolus hybrid Zefir (leaves), and Iris hungarica (rhizomes) were among the Iridaceae species used in the study. All of the extracts tested were able to kill tumour cell lines in vitro in a dosage and time-dependent manner. Their tumor-cell-killing action was tissue-specific. The HCT116 colon adenocarcinoma cell line and the HL-60 acute promyelocytic leukaemia cell line were shown to be the most susceptible to treatment with the plant extracts investigated. The extracts were shown to be ineffective against HaCaT line normal human epidermal keratinocytes. In vitro, gladiolus leaf extract has very potent anticancer effects.

Anti-cancer activity; Iridaceae; dry extracts; leaves; Crocus

"EXAMINE ANTICANCER REAGENTS OF IRIDACEAE PLANT ON HUMAN TUMOR CELLS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 10, page no.315-320, October-2018, Available :http://www.jetir.org/papers/JETIR1810A98.pdf

"EXAMINE ANTICANCER REAGENTS OF IRIDACEAE PLANT ON HUMAN TUMOR CELLS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 10, page no. pp315-320, October-2018, Available at : http://www.jetir.org/papers/JETIR1810A98.pdf