UGC Approved Journal no 63975(19)

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Published in:

Volume 5 Issue 11
December-2018
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1812C56


Registration ID:
200784

Page Number

373-377

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Title

TO COMPARE THE EFFECTIVENESS OF FRACTIONATED AND UNFRACTIONATED MALARIA INFECTED ERYTHROCYTES

Authors

Abstract

Abstract: In this study, the effectiveness of Unfractionated blood (% parasitemia was around 35%) as well as fractionated / treated/ purified infected erythrocytes (% parasitemia was around 80-90%) was compared. For this, the infected erythrocytes were separated from the blood by Percoll density gradient method. This infected cells rich fraction i.e Fractionated infected erythrocytes were having around 80% infected cells. The viability of fractionated infected erythrocytes was checked by dye exclusive test and were found to be 90%. For dose preparation, the volume of dose in case of unfractionated suspension was more as normal cells were also there (as % parasitemia was 35%). Where as in case of fractionated suspension, the % parasitemia was 80-85%, so the dose was mainly comprised of infected erythrocytes, thus the volume of dose was also comparatively less. Both the above preparations i.e unfractionated blood as well as fractionated infected erythrocytes (having 1x107 infected erythrocytes each) were injected in two mice and noted the infection pattern till the death of the animal.The dose prepared by using fractionated erythrocytes was found to be equally effective.

Key Words

Malaria, P. berghei, infected erythrocytes, parasitemia.

Cite This Article

"TO COMPARE THE EFFECTIVENESS OF FRACTIONATED AND UNFRACTIONATED MALARIA INFECTED ERYTHROCYTES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 11, page no.373-377, December 2018, Available :http://www.jetir.org/papers/JETIR1812C56.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"TO COMPARE THE EFFECTIVENESS OF FRACTIONATED AND UNFRACTIONATED MALARIA INFECTED ERYTHROCYTES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 11, page no. pp373-377, December 2018, Available at : http://www.jetir.org/papers/JETIR1812C56.pdf

Publication Details

Published Paper ID: JETIR1812C56
Registration ID: 200784
Published In: Volume 5 | Issue 11 | Year December-2018
DOI (Digital Object Identifier):
Page No: 373-377
Country: Chandigarh, Chandigarh, India .
Area: Biological Science
ISSN Number: 2349-5162
Publisher: IJ Publication


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