• Prajakta Velankar
• Sara
• Yukti Thakkar

By and by the world is in a battle with the diseases like Malaria and Dengue with no prompt medicines accessible the scourge brought about by the Malaria and Dengue is expanding step by step. A ton of researchers are continuing for the potential medication up-and-comer that could help the medical care framework in this battle. We present a docking‐based screening using a quantum mechanical scoring of a library built from approved drugs ie Remdesivir, Hydroxy-chloroquine, Curcumin, Moroxydine, Artesunate Sulphate, Mefloquine, Doxycycline, Atovaquone, Indinavir, and compounds that are with Malaria and Dengue Mpro Proteins could display antiviral activity against these diseases. Clearly, these compounds should be further evaluated in experimental assays and clinical trials to confirm their actual activity against the disease. We hope that these findings may contribute to the rational drug design against Malaria and Dengue.

Malaria, Dengue, Drug Repurposing, Computer Aid Drug Design, In silico drug development

"Drug Repurposing for Malaria and Dengue using Computational Modelling.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 12, page no.2473-2484, December-2020, Available :http://www.jetir.org/papers/JETIR1905U47.pdf

"Drug Repurposing for Malaria and Dengue using Computational Modelling.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 12, page no. pp2473-2484, December-2020, Available at : http://www.jetir.org/papers/JETIR1905U47.pdf