• Sunil Kumar
• Raman Kumar

The green processes have resulted through use of less or no catalyst, readily recyclable solvents and yield that are often higher than conventional method. Microwave heating produces heat in entire material in the same rate and the same time at a high speed and at a high rate of reaction On the basis current growing awareness around the area of environmental pollution in nature and environmental legislation, the current time have witnessed a phenomenal increasing order in the application of microwave irradiation in organic reaction synthesis. Microwave heating produces heat in entire material in the same rate and the same time at a high speed and at a high rate of reaction. Heterocyclic aromatic compounds are abundant in nature and are of great significance in life because their structural units are highly used in many natural products such as vitamins, hormones, and antibiotics; hence, they have attracted considerable attention in the design of biologically active molecules and advanced area of organic chemistry. Microwave assisted synthesis has become an important tool to the medicinal chemist for rapid organic synthesis. The microwave reactions were performed using microwave assisted synthesis on microwave, the reactions were worked up extensively to obtain a pure form of product which was isolated using literature work-up procedures. The products were further recrystallized with suitable organic solvents. The application of molecular diversity technique to drug discovery is a multidisciplinary effort in organic synthesis. Medicinal chemistry concerns with the discovery, development, interpretation and the identification of mechanism of action of biologically active compounds at the molecular level. On the basis of above reports and as part of our research programmed for development of eco-friendly synthetic protocol for biologically active compounds as well as in pursuing of our work on new solvent-free cyclisation process in different area of organic chemistry .

Green chemistry, microwave irradiation, microwave reactions, , microwave assisted reactions , Cyclisation, Active compounds.

"Eco-Friendly Synthesis and Antimicrobial and Antibacterial Evaluation of thiazolo pyridine.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 12, page no.971-973, December-2019, Available :http://www.jetir.org/papers/JETIR1912131.pdf

"Eco-Friendly Synthesis and Antimicrobial and Antibacterial Evaluation of thiazolo pyridine.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 12, page no. pp971-973, December-2019, Available at : http://www.jetir.org/papers/JETIR1912131.pdf