• Diana Seri Menina Ginting

Objective : This study is an analytical study with an experimental design, namely the Post Test Only Control Group Design, which assesses the effectiveness of administering Propolis to mice infected with vulvovaginal candidiasis Methods : This research was conducted at the Animal House of USU's FK and Microbiology Laboratory at USU Hospital. This research was conducted from 27 November to 7 December 2019. The study population was 36 experimental mice infected with vulvovaginalis candidiasis . The Collony Forming Unit (CFU) was examined on 36 rats divided into 2 groups, namely control and treatment and then examined by CFU every day from Day 0 to Day 4. The data obtained was assessed by the Mann Withney hypothesis test Results : D ari 36 samples were divided into 2 groups found in group A, which did not receive Propolis, found the number of CFU from day zero until the fourth day was 92.22 CFU , 128.89 CFU , 78.67 CFU , 56.61 CFU , and 51.61 CFU . Whereas in Group B that received Propolis , there was a mean Colony Forming Unit (CFU ) that declined from zero to fourth day, namely 97.56 CFU , 15.06 CFU, 2.61 CFU, 0.5 CFU , and on last day obtained 0 CFU . Topical propolis is effective in treating Vulvovaginal Candidiasis (KVV) in experimental model mice where the administration of Propolis can reduce the amount of CFU in the rat's vagina from day to day. Conclusion : Topical propolis is effective to reduce the number of CFUs in rats infected with vulvovaginal candidiasis (KVV)

Propolis, Topical, Vulvovaginal Candidiasis (KVV), Colony Forming Unit (CFU)

"The Effectiveness of Topical Propolis Administration in the Treatment of Vulvovaginal Candidiasis in Mouse Model Experiments", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 2, page no.1224-1228, February-2020, Available :http://www.jetir.org/papers/JETIR2002174.pdf

"The Effectiveness of Topical Propolis Administration in the Treatment of Vulvovaginal Candidiasis in Mouse Model Experiments", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp1224-1228, February-2020, Available at : http://www.jetir.org/papers/JETIR2002174.pdf