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Published in:

Volume 7 Issue 2
February-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2002178


Registration ID:
226754

Page Number

1243-1250

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Title

Correlation Between Serum Leptin Levels with Onset of Menarche

Authors

Abstract

ABSTRACT Background: One of important factor that influences the earlier onset of menarche in children is higher leptin levels. The higher the level of leptin, the earlier onset of menarche. Early onset of menarche has a negative effect in the form of a faster cessation of height due to closure of the epiphyse plate causing a low height and is believed to be a future risk for ovarian and breast cancer. Obesity that occurs during childhood is associated with the risk of long-term health problems including hypertension, diabetes mellitus, infertility, dyslipidemia and psychosocial problems. Objective: Analyze the correlation between serum leptin levels with onset at menarche. Methods: This research is an observational descriptive study with a case series design where the case is a student aged 10-14 years who has experienced menarche at the Gusti Wijaya School in Medan, North Sumatra , Indonesia . Data is collected from December 2019 until the sample is fulfilled. This study uses a sample of 30 people by simple random sampling. Subjects were measured in body mass index (BMI) and pelvic waist circumference ratio (WHR). Serum leptin levels were examined by conducting laboratory tests on venous blood using the ELISA (Enzyme Linked Immunosorbent Assay) method. Then data is collected and analyzed using statistical analysis. Results: In this study a negative correlation was obtained between serum leptin levels and age of menarche (p = 0.0001; r = -0.962). There is a correlation between serum leptin levels with BMI (p = 0.0001; r = 0.876). There is a correlation between serum leptin levels with WHR (p = 0.002; r = 0.542). Conclusion: The higher the level of serum leptin, the lower the onset of menarche, with a very strong correlation. There is a correlation between serum leptin levels with BMI and WHR.

Key Words

Serum Leptin, Menarche , BMI, WHR

Cite This Article

"Correlation Between Serum Leptin Levels with Onset of Menarche ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 2, page no.1243-1250, February-2020, Available :http://www.jetir.org/papers/JETIR2002178.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Correlation Between Serum Leptin Levels with Onset of Menarche ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp1243-1250, February-2020, Available at : http://www.jetir.org/papers/JETIR2002178.pdf

Publication Details

Published Paper ID: JETIR2002178
Registration ID: 226754
Published In: Volume 7 | Issue 2 | Year February-2020
DOI (Digital Object Identifier):
Page No: 1243-1250
Country: Medan, North Sumatera, Indonesia .
Area: Medical Science
ISSN Number: 2349-5162
Publisher: IJ Publication


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