• Dr. Alok Chandrayan
• Preeti Sharma

A simple and rapid spectroscopic, spectrophotometric and conductometric methods for the determination of Oxovanadium(IV) is developed in the presence of 2-methyl-4-(N-cyanoethyl) –N-benzenesulphonyl benzylidene-3-oxo-[N-(4-nitro-1-phenyl) propanamido] hydrazone (MNPH) under alcohalic medium. The metal ion forms dark blue coloured, λ max at 510nm. Beer’s law is obeyed in the range 0-10 mg/ml. The stoichiometry of the complex has been determined by spectrophotometric and conuctometric methods. 2-methyl-4-(N-cyanoethyl) –N-benzenesulphonyl benzylidene-3-oxo-[N-(4-nitro-1-phenyl) propanamido] hydrazone (MNPH) an biologically active compound forms 2:1 complex with molybdenum in alcohalic medium indicated by conductometric titration and is further verified by Job’s methods of continuous variation as modified by Turner and Anderson. Analytical results also favour 2:1 ratio between ligand and metal, complex of hydrazone were synthesised with molybdenum, isolated in pure form dried and weighed. The yield of the complex so obtained is substantial. Analytical data agrees with the composition [VO.L2] (where L=different new synthesised hydrazones). The applicability of the method has been tested by analysis of a large number of different synthetic and commercial samples. The characterization of these newly synthesized hydrazones and their metal complexes were done by IR, 1H-NMR spectral studies and elemental analysis. The infrared data of these complexes revealed the bidentate nature of the ligands and coordination to imino nitrogen of the amido group and azomethinic-nitrogen atoms. The new products were synthesized and evaluated for anti-tuberculosis activity against Mycobacterium tuberculosis H37RV in L.J.medium. The biological screening data indicates that the metal chelates are more potent than the parent ligands.

Spectroscopic, spectrophotometric, conductometric analysis,Job’s methods, Oxovanadium - hydrazone complex.

"Spectroscopic, Spectrophotometric and Conductometric Analysis of Oxovanadium- Hydrazone Complex", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 4, page no.429-433, April 2020, Available :http://www.jetir.org/papers/JETIR2004550.pdf

"Spectroscopic, Spectrophotometric and Conductometric Analysis of Oxovanadium- Hydrazone Complex", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 4, page no. pp429-433, April 2020, Available at : http://www.jetir.org/papers/JETIR2004550.pdf