Abstract
Invitro Screening Parameters of Citrullus Colocynthis & Citrullus Lanatus - Research Article
Mr. Harinderjit Singh1* and Hayat M Mukhtar2
1 Research Scholar, Department of Pharmaceutical Sciences, I.K.Gujral Punjab Technical University Jalandhar, Kapurthala (144603) Punjab, India.
2 Professor & Director, Shaheed Bhagat Singh College of Pharmacy, Patti (Taran Taran), Amritsar (143416) Punjab, India.
Corresponding Author: 2 Professor & Director, Shaheed Bhagat Singh College of Pharmacy, Patti (Taran Taran), Amritsar (143416) Punjab, India.
Email: harindersidhu10@mail.com.
Abstract:
Citrullus colocynthis & Citrullus lanatus has been widely used in the preparations of folk medicine since ages. Citrullus colocynthis & Citrullus lanatus has the traditional use in remedy for various diseases like Adrenocarcenoma, endothelioma, leukemia, tumors of the liver, spleen etc. A decoction of the whole plant is made with juices used to help indurations of the kidney & liver. Roots may also be used as a digestive, purgative and for treatment of jaundice, urinary diseases, rheumatism and for snake poison. ( Edogo et al., 2005; Mann et al., 1978 ;Vasu et al.,2009). The leaves are diuretic and used in the treatment of jaundice and asthma.(Cowan et al.,1999;Criagg et al.,2001). This plant is available in wild in the sandy lands of North West Punjab, Rajasthan, and southern coastal areas of India. Citrullus colocynthis & Citrullus lanatus commonly known as the colocynth, bitter apple, bitter cucumber and kaurtumba. It is a desert plant native to the Mediterranean basin and Asia. It resembles a common watermelon vine, bears, small, hard fruit with a bitter pulp. Lipoxygenase inhibitors may lead to the design of biologically and pharmacologically targeted inhibiting therapeutic strategies. Evaluation of Citrullus species extracts as a lipoxygenase inhibitor may be useful in cancer treatment. (Pontiki et al., 2008; Scheider et al., 2005). Evaluation of the fruit extract as a Inhibitor of hyaluronidase activity can be useful in the treatment of allergic reaction, reptiles (snake) bite poisoning, dengue and edema .(Martin et al.,2007; Maedea et al., 1990)