• Rizky Fachriza

This research supposed to be assessing the correlation between Estradiol levels and urine levels of Monocyte Chemotactic Protein-1 (MCP-1) in menopausal patients with Overactive Bladder at H Adam Malik General Hospital Medan. This research was an observational analytic study with a case series research design to assess the correlation between Estradiol levels and urine urine Monocyte Chemotactic Protein-1 (MCP-1) in postmenopausal women with overactive bladder. The sample was all menopausal female paramedics with overactive bladder at H Adam Malik General Hospital Medan who met the inclusion and exclusion criteria using non-probability methods with consecutive sampling technique. All data collected is then analyzed. Data were analyzed using the Pearson correlation test if the data were not normally distributed and the Speramen test if the data were not normally distributed. A p value of less than 0.05 was considered significant with 95% CI. From the results of the study found the characteristics of OAB patients. primipara, sekundipara and multipara 1 (2.9%), sekundipara 13 (38.2%) and 20 (58.8%). Based on normoweight and overweight as many as 6 (17.6%) and 28 (82.4%), menopause, 2-3 years, 4 years, and 5 years respectively 20 (58.8%), 12 (35, 3%), and 2 (5.9%), age, 40-49 years and 50 - 59 years, respectively 2 (5.9%) and 32 (94.1%). the value of urinary MCP 1 was based on a mild, moderate, OABSS score of 65.14 ± 96.11; 34.10 ± 46.15; 41.28 ± 61.59 from the spearmen correlation test found a very strong negative correlation correlation coefficient -0.682; p <0.001. The mean urine urine estradiol sample was 24.26 ± 5.73 (154-37.8). urine MCP 1 value based on a mild, moderate OABSS score of 92.81 ± 4.44; 108.53 ± 10.21; 156 ± 10.21; Spearmen correlation test obtained a correlation coefficient value of 0.856; p <0.001. Estradiol correlation with urine Monocyte Chemotactic Protein-1 (MCP-1) in postmenopausal women with overactive bladder r value -0.658. There is a negative correlation between Estradiol levels and urine urine Monocyte Chemotactic Protein-1 (MCP-1) in menopausal women with overactive bladder

Overactive bladder, OAB, Monocyte Chemotactic Protein-1, MCP-1, Menopause

"CORRELATION OF ESTRADIOL WITH MONOCYTE CHEMOTACTIC PROTEIN-1 (MCP-1) URINES LEVELS ON MENOPAUSAL WOMEN WITH OVERACTIVE BLADDER", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 8, page no.160-164, August-2020, Available :http://www.jetir.org/papers/JETIR2008019.pdf

"CORRELATION OF ESTRADIOL WITH MONOCYTE CHEMOTACTIC PROTEIN-1 (MCP-1) URINES LEVELS ON MENOPAUSAL WOMEN WITH OVERACTIVE BLADDER", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 8, page no. pp160-164, August-2020, Available at : http://www.jetir.org/papers/JETIR2008019.pdf