• Surg Lt Cdr (Dr) Goutam Nanavati
• Col (Dr) T Prasanth
• Lt Col (Dr) Satisha TS
• Maj (DR) Pamil Banotra

Periodontal disease is a chronic inflammatory disease of the supporting structures of tooth and is related to the oxidative state of the tissue. In its most common form, chronic periodontitis (CP) is initiated by the microorganisms which are a part of the dental biofilm, causing a local host immune response which results in host mediated tissue destruction and unresolved inflammation. This condition occurs usually in individuals with a tendency towards high rate of accumulation of plaque and calculus deposits in the oral cavity. In the prolonged presence of deposits, the tissue is further exposed to bacterial endotoxins, which leads to the inflammatory responses in the host. These endotoxins cause heightened oxidative stress and discharge of reactive oxygen species. There exists a natural dynamic state of equilibrium between reactive oxygen species (ROS) and antioxidants (AOs). Any disruption in one would lead to modification in the value of other. The values of antioxidant enzymes like Superoxidase dismutase (SOD) and Glutathione (GSH) are thus affected during periodontitis. Instituting periodontal therapy, reduces the levels of these ROS considerably, thus limiting the tissue damage and leading to resolution of the inflammation.

Antioxidants; Periodontal disease; Periodontitis; Oxidative stress

"ROLE OF ANTIOXIDANTS AS AN ADJUNCT IN TREATMENT OF PERIODONTAL DISEASE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 4, page no.251-261, April-2021, Available :http://www.jetir.org/papers/JETIR2104133.pdf

"ROLE OF ANTIOXIDANTS AS AN ADJUNCT IN TREATMENT OF PERIODONTAL DISEASE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 4, page no. pp251-261, April-2021, Available at : http://www.jetir.org/papers/JETIR2104133.pdf