UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 8 Issue 5
May-2021
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2105205


Registration ID:
309043

Page Number

b571-b578

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Title

Formulation, Development and Evaluation of Fast Dissolving Tablets containing Azilsartan medoxomil

Abstract

The aim of the study was to formulate develop and evaluate fast dissolving tablets of Azilsartan medoxomil. Azilsartan medoxomil is an angiotensin II receptor antagonist used in the treatment of hypertension. It is having less side effects as compared to other angiotensin receptor antagonist. Azilsartan medoxomil is having low solubility hence solubility was enhanced by solubility enhancement technique. Solid dispersion was prepared by using Poloxamer 188 for solubility enhancement. The preliminary trials were performed by using different superdisintegrants. Plantago ogata was used as superdisintegrant in combination with crosspovidone. The prepared formulation was then evaluated by using various parameters. Finally it was concluded that the formulated fast dissolving tablets have good dissolution characteristics as compared to that of pure drug.

Key Words

Fast dissolving tablets, Hypertension, Poloxamer 188, Plantago ovata, Solubility enhancement technique, Solid dispersion.

Cite This Article

"Formulation, Development and Evaluation of Fast Dissolving Tablets containing Azilsartan medoxomil ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 5, page no.b571-b578, May-2021, Available :http://www.jetir.org/papers/JETIR2105205.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Formulation, Development and Evaluation of Fast Dissolving Tablets containing Azilsartan medoxomil ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 5, page no. ppb571-b578, May-2021, Available at : http://www.jetir.org/papers/JETIR2105205.pdf

Publication Details

Published Paper ID: JETIR2105205
Registration ID: 309043
Published In: Volume 8 | Issue 5 | Year May-2021
DOI (Digital Object Identifier):
Page No: b571-b578
Country: Bhilad. Dist: Valsad, Gujarat , India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


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