• Benjamin Sihite
• Indra G. Munthe
• Hotma P. Pasaribu
• Sarma N. Lumbanraja
• Hanudse Hartono

Introduction: Preeclampsia is an important complication of pregnancy that affects about 2-8% and is characterized by the presence of placental dysfunction due to systemic inflammation. One of the widely used inflammatory markers is high sensitivity C-Reactive Protein (hs-CRP) which is produced by a hypoperfused placenta in preeclampsia. The purpose of this study was to determine the comparison of hs-CRP levels in preeclampsia and normal pregnancies. Methods: This study is an observational analytic study with a case-control design which was conducted at the Adam Malik General Hospital and network hospitals from February until the number of samples was met. The study subjects were normal pregnant women and preeclampsia in the third trimester who visited the polyclinic. All study subjects underwent history taking, physical examination, and hs-CRP examination through blood samples from the median cubital vein. After data collection was completed, the data were analyzed using the Mann-Whitney test. Results: This study was followed by 60 study subjects consisting of normal pregnant women and preeclampsia. Study subjects in the preeclampsia group had a higher mean parity, age, gestational age, body mass index, blood pressure and mean arterial pressure than the group of normal pregnant women and found a positive correlation between these variables and hs-CRP levels. Examination of hs-CRP levels in preeclampsia patients was also higher than in normal pregnant patients and there was a significant difference between the two groups (p = 0.000). Conclusion: There was a significant difference between hs-CRP levels in preeclampsia patients with normal pregnant patients and significantly higher hs-CRP levels were found in the preeclampsia group (p<0.05).

Preeclampsia, high sensitive c-reactive protein, inflammation

"Comparison Between High Sensitive C-Reactive Protein (HS-CRP) Level In Preeclamptic Woman and Normal Pregnancy", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 6, page no.c149-c155, June-2021, Available :http://www.jetir.org/papers/JETIR2106290.pdf

"Comparison Between High Sensitive C-Reactive Protein (HS-CRP) Level In Preeclamptic Woman and Normal Pregnancy", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 6, page no. ppc149-c155, June-2021, Available at : http://www.jetir.org/papers/JETIR2106290.pdf