UGC Approved Journal no 63975

ISSN: 2349-5162 | ESTD Year : 2014
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Volume 9 | Issue 8 | August 2022

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Published in:

Volume 8 Issue 7
July-2021
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2107349


Registration ID:
312460

Page Number

c614-c617

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Title

Effect of Aqueous and ethyl acetate extracts of Acanthospermum hispidum on Streptozotocin induced diabetic animals

Abstract

The present study evaluated the anti-hyperglycemic activity of the Ethyl acetate extract of Acanthospermum hispidum on blood glucose, Plasma insulin and glycoprotein contents of albino rats. AHEt was administered at doses of 150, 300 and 450 mg/kg body weight respectively on stz induced diabetic rats for 2 weeks. The aim of this study was to investigate the effect of ethanolic extract of Acanthospermum hispidum (AHEt) in stz induced diabetic, which was induced in male albino Wistar rats by a single intra peritoneal injection of streptozotocin (55 mg/kg). After injection, the animals were divided into five groups viz., control group, AHEt (300mg/kg) treated group, diabetic group, diabetic + AHEt (450mg/kg) body weight for 2 weeks .The study shows a significant increase in the levels of blood glucose, and plasma glycoproteins, while plasma insulin levels were significantly decreased in diabetic rats. There was also a significant decrease in the level of sialic acid and elevated levels of hexose, hexosamine in the liver and kidney of diabetic rats. The diabetic animals also showed a reduction of body weights. Oral administration of AHEt reverted these changes. Thus the study indicates that Acanthospermum hispidum. possesses a significant beneficial effect on glycoprotein's in addition to its antidiabetic action.

Key Words

hypoglycemic activity, Acanthospermum hispidum, Ethyl acetate extract

Cite This Article

"Effect of Aqueous and ethyl acetate extracts of Acanthospermum hispidum on Streptozotocin induced diabetic animals", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 7, page no.c614-c617, July-2021, Available :http://www.jetir.org/papers/JETIR2107349.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Effect of Aqueous and ethyl acetate extracts of Acanthospermum hispidum on Streptozotocin induced diabetic animals", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 7, page no. ppc614-c617, July-2021, Available at : http://www.jetir.org/papers/JETIR2107349.pdf

Publication Details

Published Paper ID: JETIR2107349
Registration ID: 312460
Published In: Volume 8 | Issue 7 | Year July-2021
DOI (Digital Object Identifier):
Page No: c614-c617
Country: Tirupati, ANDHRA PRADESH, India .
Area: Science
ISSN Number: 2349-5162
Publisher: IJ Publication


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