• Akash S. Malthankar
• Gaurav G. Manwar
• Rahul S. Khalelkar

Approximately 74 % of medicines currently administered orally and are found to be ineffective. The strategy of Transdermal Drug Delivery has full-grown in quality as a viable alternative to systemic drug administration. Transdermal Drug Delivery System technologies have currently been created and are thought to be helpful within the rate-controlled delivery of that are difficult to administer. The transdermal delivery has an advantage over injectable and oral delivery as a result of it improves patient compliance and avoids first-pass metabolism. Transdermal administration of drug could be a another technique of delivery that may significantly transport larger molecules in strong amounts, overcoming problems with oral administration like restricted bioavailability due to first-pass metabolism, which may result in fast blood level increase (both high and low). Transdermal medicines have the potential to boost the efficiency and safety of prescribed drugs. The patch delivers medication to the patient during a controlled manner, typically, a porous membrane covering a drug reservoir or body heat melting thin layers of medication incorporated within the adhesive are used, that is an advantage of transdermal drug delivery over alternative methods like oral, topical, intravenous drug delivery and so on. Transdermal medication delivery could be a comparatively new technology with a bright future. It has the potential to reduce the requirement of needles within the administration of a wide range of medication, however the cost component is essential. This article offers a general summary of the transdermal Drug Delivery System (TDDS), its advantages & disadvantages, factor affecting transdermal drug delivery and types of transdermal patches are also added here.

Transdermal drug delivery, bioavailability, first-pass metabolism, intravenous drug delivery.

"A Brief Review On: Transdermal Drug Delivery System ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 9, page no.c537-c541, September-2021, Available :http://www.jetir.org/papers/JETIR2109271.pdf

"A Brief Review On: Transdermal Drug Delivery System ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 9, page no. ppc537-c541, September-2021, Available at : http://www.jetir.org/papers/JETIR2109271.pdf