• Sangram G. Nagargoje
• Laxmi B. Dhotre

Powerful new technologies such as high-throughput screening and combinatorial chemistry are revolutionizing drug discovery. Combinatorial chemistry has become an important part of the discovery and optimization process for novel drugs, affinity ligands, and catalysts. Socya nide-based multi component reactions (MCR's) markedly differ from their usual two component counter parts. Combinatorial chemistry has given chemists access to vast numbers of molecules, but selecting the right one has proved more difficult. I express my thanks to the authors who contributed the careful and thorough reviews presented in this volume. The various methods of establishing the identity of the winners constitute the set of useful encoding strategies. In their Perspective, Lehn and Eliseev chart some of the recent progress in this field. This review highlights some of the strengths of large library combinatorial chemistry as a means of generating molecules for lead discovery, such as providing rich and robust structure-activity relationships around each hit series-I express my thanks to the authors who contributed the careful and thorough reviews presented in this volume.

Community Policing, Combinatorial, synthesis, Drug Discovery.

"Combinatorial chemistry", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 1, page no.e107-e109, January-2022, Available :http://www.jetir.org/papers/JETIR2201415.pdf

"Combinatorial chemistry", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 1, page no. ppe107-e109, January-2022, Available at : http://www.jetir.org/papers/JETIR2201415.pdf