• Vivek Kumar Singh
• Dr. Praveen Kumar Ashok
• Ms. Gulfsha Parveen

As it is well known that contamination is major concern in pharmaceutical industry. There are various factors which possibly cause contamination in pharma industry, and one of such factor is improper cleaning, improper cleaning of processing area, equipment, and apparatus which can leads to severe hazards. Hence, it’s a major concerned to have proper cleaning procedure. Pharmaceutical products can be contaminated by other pharmaceutical product or API, or by other cleaning agent, dust particles, and previous batches. Because of this, pharma industries always ensure that cleaning procedures are strictly followed and validated. In cleaning validation different parameters, material, process controls are monitored and validated so that a consistent cleaning procedure can be develop and documented. Apart from commercial procedures like matrix there are various advancements comes in existence in cleaning validation procedure like safety factor API acceptance limit.

CV: Cleaning Validation, MAC: Maximum Allowable Carryover

"APPROACHES AND ADVANCES IN CLEANING VALIDATION ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 1, page no.f64-f76, January-2022, Available :http://www.jetir.org/papers/JETIR2201513.pdf

"APPROACHES AND ADVANCES IN CLEANING VALIDATION ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 1, page no. ppf64-f76, January-2022, Available at : http://www.jetir.org/papers/JETIR2201513.pdf