UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Volume 9 Issue 3
March-2022
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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JETIR2203098


Registration ID:
320991

Page Number

a810-a822

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Title

FORMULATION AND EVALUATION OF TINOSPORA CORDIFOLIA POWDER AND GRANULES

Abstract

Giloy is considered one of the best medicines in Ayurveda for treating various fevers and other ailments. One of the three Amrit plants is Giloy. Amrit is the Sanskrit word for "source of immortality." As a result, it's also known as Amritavalli or Amrita in Sanskrit.. [1] Since time immemorial, Guduchi (Tinospora cordifolia (Willd.) Miers) has been a highly appreciated plant in the Ayurvedic system of treatment. The essence or active part of a herb is called Satva or Sara, and it refers to the aqueous extractable solid substance gathered from herbal drugs. Guduchi Satva (a whitish starch-like material produced from Tinospora cordifolia) is widely suggested in diseases like Jwara (fever), Daha, and other herbal Satvas.The raw substance was collected between the months of December and January, as this is when more Satva is extracted. The Guduchi plant growing on Nimba was chosen since it is said to be the best because the synergy between these plants increases their potency. Yadavji Trikamji, Acharya, has mentioned use ‘Angustha pramana’ (thumb size) of Guduchi stem,accordingly thumb sized or medium size stem diameter (1.6‑2.0 cm) was selected for study, as it is reported to yield more powder (Satva)..[2] The microscopy of Tinospora cordiofollia stem was performed and the several components of the T.S of stem like sclerenchyma cells,cortex,fibers,xylem vessels were observed under microscope.Test for identification of Microscopical character Eg. Iodine test, Conc.HCL+phloroglucinol test, HCl test, 60% sulphuric acid test was done. The white starch material from the giloy stem was extracted and filtered , dried and converted in the form of fine powder of 2.24g .The powder is further used for granulation process.The Gum Tragacanth and Accaia are the binders used in formulation as binding agent with the distilled water and API and act as the additive in formulation . The standard formulation for granulation with Acacia is available in certain refrences .Tragacanth provides thixotrophy to a solution (forms pseudoplastic solutions). The maximum viscosity of the solution is achieved after several days, due to the time taken to hydrate completely. Tragacanth is stable at a pH range of 4-8.It is a better thickening agent than acacia.Tragacanth is used as a suspending agent, emulsifier, thickener, and stabilizer. The gum solution is stable under acid conditions and shows good emulsification characteristics.Hence ,Gum Acacia is replaced by Tragacanth. By alteration of binding agent there is no change in granules size, texture,appearance ..[3] The weight of granules from the white powder is 1.203g. The evaluation parameters for powder and granules like the tap-density, Bulk-density , carr's index, Hausnners ratio , Angle of repose were performed. The prepared granules were filled and stored in wide mouth glass container .

Key Words

giloy, ayurvedic, powder, granules, tragacanth

Cite This Article

"FORMULATION AND EVALUATION OF TINOSPORA CORDIFOLIA POWDER AND GRANULES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 3, page no.a810-a822, March-2022, Available :http://www.jetir.org/papers/JETIR2203098.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"FORMULATION AND EVALUATION OF TINOSPORA CORDIFOLIA POWDER AND GRANULES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 3, page no. ppa810-a822, March-2022, Available at : http://www.jetir.org/papers/JETIR2203098.pdf

Publication Details

Published Paper ID: JETIR2203098
Registration ID: 320991
Published In: Volume 9 | Issue 3 | Year March-2022
DOI (Digital Object Identifier):
Page No: a810-a822
Country: Mumbai, Maharashtra, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


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