• Naramdasu Vijay
• Shaik.Azeez
• Kondapalli chandra ganesh
• Paluri gopi krishna reddy
• Chinnapureddy .chandrasekhar reddy

A rapid and stability-indicating ultra-performance liquid chromatography method was developed for quantification of Nebivolol, Valsartan, Ezetimibe, Atorvastatin, Canagliflozin to get some more advantages over other methods already developed in different methods we can single method. The method was developed according to ICH and to develop the calibration curve for all drugs using this method. In this method a simple isocratic conditions of mobile phase comprising 0.1% TFA and methanol in a ratio of 30:70, v/v at a flow rate of 0.5 mL/minute over kinetex C18, 100 × 4.6 mm, 2.6μm column at room temperature was maintained. The method showed excellent linear response with correlation coefficient (R2 ) values of 0.999 for Nebivolol, Valsartan, Ezetimibe, Atorvastatin, Canagliflozin which was within the limit of correlation coefficient (R2 ≥ 0.995).

UPLC, Nebivolol, Valsartan, Ezetimibe, Atorvastatin, Canagliflozin.

"AN COMMON TECHNIQUE WAS APPLIED FOR CARDIOVASCULAR DRUGS RECOVERIESIN SAME MOBILE PHASE IN DIFFERENT TYPES COLUMNS BY UPLC METHOD", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 3, page no.f566-f575, March-2022, Available :http://www.jetir.org/papers/JETIR2203571.pdf

"AN COMMON TECHNIQUE WAS APPLIED FOR CARDIOVASCULAR DRUGS RECOVERIESIN SAME MOBILE PHASE IN DIFFERENT TYPES COLUMNS BY UPLC METHOD", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 3, page no. ppf566-f575, March-2022, Available at : http://www.jetir.org/papers/JETIR2203571.pdf